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CAS 51706-40-2

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Atenolol hydrochloride

Description:
Atenolol hydrochloride is a selective beta-1 adrenergic antagonist primarily used in the treatment of hypertension and certain heart conditions, such as angina and arrhythmias. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range of approximately 4.5 to 6.5 in solution. The molecular formula of atenolol hydrochloride is C14H22N2O3S·HCl, and it has a molecular weight of around 266.8 g/mol. This compound works by blocking the effects of adrenaline on the heart, leading to a decrease in heart rate and blood pressure. Atenolol is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. It is important to monitor patients for potential side effects, which may include fatigue, dizziness, and gastrointestinal disturbances. Atenolol hydrochloride is contraindicated in certain conditions, such as severe bradycardia and asthma, due to its effects on the cardiovascular and respiratory systems.
Formula:C14H22N2O3·ClH
InChI:InChI=1S/C14H22N2O3.ClH/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18;/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18);1H
InChI key:InChIKey=FFDDLJYKJQGSPW-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(CC(N)=O)C=C1.Cl
Synonyms:
  • dl-Atenolol hydrochloride
  • Atenolol hydrochloride
  • Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, monohydrochloride
  • Tenormine hydrochloride
  • Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, hydrochloride (1:1)
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