CAS 5171-37-9

Isopteropodine

Description:

Isopteropodine, with the CAS number 5171-37-9, is a chemical compound that belongs to the class of alkaloids. It is primarily derived from certain plant species and is known for its potential biological activities. The compound typically exhibits a complex structure, which may include multiple rings and functional groups that contribute to its reactivity and interaction with biological systems. Isopteropodine has been studied for its pharmacological properties, including potential effects on the central nervous system and its role in traditional medicine. Its solubility, stability, and reactivity can vary depending on the conditions, such as pH and temperature. As with many alkaloids, it may possess both therapeutic benefits and toxicological concerns, necessitating careful handling and further research to fully understand its mechanisms of action and potential applications in medicine. Overall, Isopteropodine represents an interesting subject of study within the field of natural products and medicinal chemistry.

Formula: C₂₁H₂₄N₂O₄

InChI: InChI=1/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14-,18?,21?/m1/s1

InChI key: InChIKey=JMIAZDVHNCCPDM-PFDNRQJHSA-N

SMILES: O=C1[C@]2([C@]3(N(CC2)C[C@@]4([C@](C3)(C(C(OC)=O)=CO[C@H]4C)[H])[H])[H])C=5C(N1)=CC=CC5

Synonyms:

• 7-Isopteropodine
• Formosanan-16-carboxylic acid, 19-methyl-2-oxo-, methyl ester, (7α,19α,20α)-
• Isopteropodin
• Isopteropodine
• Spiro[3H-indole-3,6'(10'H)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,4'a,5',5'a,7',8',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'R,4a'R,10a'R)-
• Spiro[3H-indole-3,6′(4′aH)-[1H]pyrano[3,4-f]indolizine]-4′-carboxylic acid, 1,2,5′,5′a,7′,8′,10′,10′a-octahydro-1′-methyl-2-oxo-, methyl ester, (1′S,3S,4′aS,5′aS,10′aS)-
• Spiro[3H-indole-3,6′(4′aH)-[1H]pyrano[3,4-f]indolizine]-4′-carboxylic acid, 1,2,5′,5′a,7′,8′,10′,10′a-octahydro-1′-methyl-2-oxo-, methyl ester, [1′S-(1′α,4′aα,5′aα,6′α,10′aα)]-
• Uncarine E
• allo-Isopteropodine
• Isopteropodine (20 mg)
• Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)-
• methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
• methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
• (7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
• Isopteropodine(Uncarine E)
• (1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
• Rhynchophylline E

Isopteropodine

CAS: 5171-37-9

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

Formula: C₂₁H₂₄N₂O₄

Color and Shape: White Solid Crystals

Molecular weight: 368.17361

Ref: 45-1351107

Uncarine E

CAS: 5171-37-9

Formula: C₂₁H₂₄N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 368.4263

Ref: IN-DA00D9SU

Isopteropodine

CAS: 5171-37-9

Formula: C₂₁H₂₄N₂O₄

Molecular weight: 368.43

Ref: 7W-GY4292

Methyl (1'S,3S,4a'S,5a'S,10a'S)-1'-methyl-2-oxo-4a',5',5a',7',8',10a'-hexahydro-1'H,10'H-spiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

CAS: 5171-37-9

Methyl (1'S,3S,4a'S,5a'S,10a'S)-1'-methyl-2-oxo-4a',5',5a',7',8',10a'-hexahydro-1'H,10'H-spiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate

Purity: 97%

Molecular weight: 368.43g/mol

Ref: 54-OR1074221

Isopteropodine

CAS: 5171-37-9

Isopteropodine (Uncarine E) is an isoyohimbine-type octindole alkaloid isolated from Hamelia patens micropropagated and has antimicrobial activity and stimulates the immune system. Isopteropodine has antimicrobial activity and stimulates the immune system.Isopteropodine is a positive modulator of muscarinic M1 and 5-HT2 receptors and a PXR activator that induces contraction of the rat myometrium.

Formula: C₂₁H₂₄N₂O₄

Purity: 97.93%

Color and Shape: Solid

Molecular weight: 368.43

Ref: TM-TN1790

Isopteropodine

CAS: 5171-37-9

Formula: C₂₁H₂₄N₂O₄

Purity: 95%~99%

Molecular weight: 368.433

Ref: BP-BP1425

Uncarine e

CAS: 5171-37-9

Natural alkaloid

Formula: C₂₁H₂₄N₂O₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 368.43

Ref: 5G-89816

Isopteropodine

Controlled Product

CAS: 5171-37-9

Applications Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.
References Rinner, B. et al.: Anticancer. Res., 29, 4519 (2009); Cheng, A. et al.: Food Chem. Toxicol., 45, 2206 (2007);

Formula: C₂₁H₂₄N₂O₄

Color and Shape: Yellow To Beige

Molecular weight: 368.43

Ref: TR-I874220

allo-Isopteropodine

CAS: 5171-37-9

Allo-isopteropodine is a monoterpenoid indole alkaloid that belongs to the group of acetate extract. It has been shown to have strong anti-cancer effects on skin cancer cells, as well as potential for treatment of cervical cancer. Allo-isopteropodine was found to inhibit 5-HT2 receptors and produce a locomotor activity in rats. This compound also inhibits the production of acetylcholine by binding to muscarinic receptors and has been shown to have a variety of physiological effects such as reducing blood pressure, increasing urine output, and lowering heart rate. Allo-isopteropodine can also be used as an analgesic and antipyretic agent.

Formula: C₂₁H₂₄N₂O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 368.43 g/mol

Ref: 3D-FI137502