CAS 51773-92-3: Mefloquine hydrochloride

Description:Mefloquine hydrochloride is an antimalarial medication primarily used for the prevention and treatment of malaria, particularly in areas where resistance to other antimalarial drugs is prevalent. It is a synthetic compound belonging to the class of quinolines and is characterized by its ability to interfere with the growth of the malaria parasite within red blood cells. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in oral form. Mefloquine hydrochloride has a relatively long half-life, allowing for once-weekly dosing in prophylactic regimens. However, it is associated with a range of potential side effects, including neuropsychiatric symptoms, which can limit its use in certain populations. The compound's mechanism of action involves the inhibition of heme polymerization, leading to the accumulation of toxic heme within the parasite. Due to its specific pharmacological profile, mefloquine hydrochloride remains an important option in the global fight against malaria, especially in endemic regions.

Formula:C₁₇H₁₆F₆N₂O·ClH

InChI:InChI=1/C17H16F6N2O.ClH/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11;/h3-5,8,12,15,24,26H,1-2,6-7H2;1H/t12-,15+;/s2

InChI key:InChIKey=WESWYMRNZNDGBX-HFEUSWDWNA-N

SMILES:Cl.FC(F)(F)C1=NC2=C(C=CC=C2C(F)(F)F)C(=C1)C(O)C3NCCCC3

Synonyms:
(2R)-(+/-)-alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride
(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol hydrochloride (1:1)
4-Quinolinemethanol, α-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-, hydrochloride (1:1), (αS)-rel-
4-Quinolinemethanol, α-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-, monohydrochloride, (αS)-rel-
4-Quinolinemethanol, α-2-piperidinyl-2,8-bis(trifluoromethyl)-, monohydrochloride, (R*,S*)-
Loriam
Mefloquin hydrochloride
Mefloquine Hcl
NSC 157387
Ro 21-5998/001
See more synonyms
Wr 142490
[2,8-Bis(Trifluoromethyl)Quinolin-4-Yl](Piperidin-2-Yl)Methanol Hydrochloride (1:1)
Mefloquine hydrochloride

Found 17 products.

Product data	Purity	Price range	Estimated delivery
Mefloquine Hydrochloride REF: 3B-M2313CAS: 51773-92-3 53230-10-7	>98.0%(HPLC)	111.00 €	Mon 07 Apr 25
Mefloquine for system suitability CRS REF: 41-Y0002421CAS: 51773-92-3	- - -	115.00 €	Mon 14 Apr 25
Mefloquine hydrochloride CRS REF: 41-M0253000CAS: 51773-92-3	- - -	115.00 €	Mon 14 Apr 25
Mefloquine Hydrochloride REF: 45-1379059CAS: 51773-92-3	- - -	463.00 €	Tue 15 Apr 25
4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,monohydrochloride, (aS)-rel- REF: IN-DA00I991CAS: 51773-92-3	%	To inquire	Mon 14 Apr 25
Mefloquine hydrochloride REF: TM-T0860CAS: 51773-92-3	99% - 99.74%	35.00 €~97.00 €	Mon 14 Apr 25
Mefloquine hydrochloride REF: 7W-GP7880CAS: 51773-92-3	≥ 98.0%	38.00 €~99.00 €	Tue 15 Apr 25
Mefloquine hydrochloride, BP, Ph. Eur., USP grade REF: 7W-GP0681CAS: 51773-92-3	- - -	340.00 €	Tue 15 Apr 25
Mefloquine HCl REF: 4Z-M-821CAS: 51773-92-3	- - -	To inquire	Tue 15 Apr 25
(S)-[2,8-Bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol hydrochloride REF: 54-PC404546CAS: 51773-92-3	98%	50.00 €~680.00 €	Tue 15 Apr 25
Mefloquine hydrochloride REF: 54-BUP13994CAS: 51773-92-3	99.65%	52.00 €~160.00 €	Tue 15 Apr 25
Mefloquine hydrochloride 100 µg/mL in Acetonitrile REF: 04-A14860900AL-100CAS: 51773-92-3	- - -	To inquire	Thu 17 Apr 25
Mefloquine Hydrochloride REF: 86-MM1198.00CAS: 51773-92-3	- - -	293.00 €	Thu 17 Apr 25
Mefloquine hydrochloride REF: 10-F091687CAS: 51773-92-3	95.0%	To inquire	Thu 24 Apr 25
Mefloquine Hydrochloride (d10 Major) REF: TR-M207053CAS: 51773-92-3	- - -	414.00 €~2,840.00 €	Thu 24 Apr 25
Mefloquine hydrochloride REF: 3D-FP40600CAS: 51773-92-3	Min. 95%	120.00 €~2,481.00 €	Fri 25 Apr 25
Mefloquine hydrochloride REF: 04-C14860900CAS: 51773-92-3	- - -	- - -	Discontinued product