CAS 51781-06-7: Carteolol

Description: Carteolol is a non-selective beta-adrenergic antagonist, primarily used in the treatment of glaucoma and ocular hypertension. It functions by reducing intraocular pressure through the inhibition of aqueous humor production. As a member of the beta-blocker class, carteolol exhibits both beta-1 and beta-2 adrenergic receptor blocking properties, which can lead to a decrease in heart rate and myocardial contractility, although its systemic effects are minimized when used topically in ophthalmic formulations. The compound is characterized by its relatively low lipophilicity, which contributes to its efficacy in the eye while limiting systemic absorption. Carteolol is typically administered as an eye drop solution and may be used alone or in combination with other antiglaucoma medications. Common side effects may include ocular irritation, dry eyes, and potential systemic effects such as bradycardia or hypotension, particularly in sensitive individuals. Overall, carteolol is an important therapeutic agent in managing elevated intraocular pressure in patients with glaucoma.

Formula: C₁₆H₂₄N₂O₃

InChI: InChI=1S/C16H24N2O3/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20)

InChI key: InChIKey=LWAFSWPYPHEXKX-UHFFFAOYSA-N

SMILES: O=C1NC=2C=CC=C(OCC(O)CNC(C)(C)C)C2CC1

Synonyms:

• Carteolol
• 5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone
• 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-
• (±)-Carteolol
• dl-Carteolol

Carteolol Hydrochloride

CAS: 51781-06-751781-21-6

• Formula: C₁₆H₂₄N₂O₃·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 328.84

Carteolol

CAS: 51781-06-7

Carteolol is a non-selective beta-adrenergic receptor antagonist. It has been used to treat high blood …

• Formula: C₁₆H₂₄N₂O₃
• Purity: Min. 95%
• Molecular weight: 292.37 g/mol