CAS 518-34-3: Tetrandrine
Description:Tetrandrine is a bisbenzylisoquinoline alkaloid primarily derived from the plant *Stephania tetrandra*, which is traditionally used in Chinese medicine. It is characterized by its complex structure, featuring two benzylisoquinoline units linked by a carbon chain. Tetrandrine exhibits a range of biological activities, including anti-inflammatory, anti-cancer, and anti-arrhythmic properties. It has been studied for its potential to modulate calcium channels, which can influence various physiological processes. The compound is typically found as a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Tetrandrine's pharmacological effects are attributed to its ability to interact with multiple cellular pathways, making it a subject of interest in both traditional and modern medicinal research. However, its use may be associated with side effects, necessitating careful consideration in therapeutic applications. As with any bioactive compound, further studies are essential to fully understand its mechanisms and potential clinical uses.
Formula:C38H42N2O6
InChI:InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1
InChI key:InChIKey=WVTKBKWTSCPRNU-KYJUHHDHSA-N
SMILES:O1C2=CC=C(C=C2)CC3C4=CC(OC=5C(OC)=C(OC)C=C6C5C(N(C)CC6)CC7=CC=C(OC)C1=C7)=C(OC)C=C4CCN3C
- Synonyms:
- (+)-Tetrandrine
- (1Beta)-6,6',7,12-Tetramethoxy-2,2'-Dimethylberbaman
- (1Beta,1'Xi)-6,6',7,12-Tetramethoxy-2,2'-Dimethylberbaman
- (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
- 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aS)-
- 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, [4aS-(4aR*,16aR*)]-
- 6,6',7,12-Tetramethoxy-2,2'-dimethyl-1-beta-berbaman
- Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1beta)-
- Berbaman, 6,6′,7,12-tetramethoxy-2,2′-dimethyl-, (1β)-
- D-Tetrandrine
- See more synonyms
- Fanchinine
- Hanfangchin A
- NSC 77037
- Sinomenine A
- Tetrandrin
