CAS 51803-78-2

Nimesulide

Description:

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its selective inhibition of cyclooxygenase-2 (COX-2), which plays a crucial role in the inflammatory process. Nimesulide is known for its relatively rapid onset of action and is often prescribed for conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. The chemical structure of nimesulide includes a sulfonamide group, which contributes to its pharmacological activity. It is typically administered orally and is available in various formulations, including tablets and suspensions. While nimesulide is effective in managing pain and inflammation, it has been associated with potential side effects, particularly concerning liver toxicity, which has led to its restricted use in some countries. As with any medication, it is essential for patients to consult healthcare professionals regarding its use, dosage, and potential risks.

Formula: C₁₃H₁₂N₂O₅S

InChI: InChI=1/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3

InChI key: InChIKey=HYWYRSMBCFDLJT-UHFFFAOYSA-N

SMILES: O(C1=C(NS(C)(=O)=O)C=CC(N(=O)=O)=C1)C2=CC=CC=C2

Synonyms:

• 2-Phenoxy-4-nitromethanesulfonanilide
• 4'-Nitro-2'-phenoxymethanesulfonanilide
• Aulin
• Flogovital
• Lizepat
• Mesulid
• Mesulide
• Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-
• Methosulide
• N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide
• Nicip
• Nimalox
• Nimed
• Nimepast
• Nimesulid
• Nimesulida
• Nimsulid
• Nimulid
• Nise*Gel
• Nise^*Gel
• Nisulid
• Nizer
• Orthobid
• R 805
• R 805 (pharmaceutical)
• Sulidan
• Sulide
• Sulidene
• 4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE
• NIMESULIDE
• n-(4-nitro-2-phenoxyphenyl)-methanesulfonamid
• Nisuli
• 4’-nitro-2’-phenoxy-methanesulfonanilid
• 4-Nitro-2-phenoxymethanesulfonamide
• Nide
• CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD)
• 4-nitro-2-phenoxy-methanesulfonanilide
• CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD)
• Nidol
• CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD)
• FANSIDOL

Nimesulide

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 308.31

Ref: 3B-N0984

Nimesulide

CAS: 51803-78-2

Highly selective cyclooxygenase-2 inhibitor which induces apoptosis

Formula: C₁₃H₁₂N₂O₅S

Molecular weight: 308.31

Ref: 02-J63699

NIMESULIDE FOR PEAK IDENTIFICATION CRS

CAS: 51803-78-2

NIMESULIDE FOR PEAK IDENTIFICATION CRS

Formula: C₁₃H₁₂N₂O₅S

Molecular weight: 308.3098

Ref: 41-Y0001237

NIMESULIDE CRS

CAS: 51803-78-2

NIMESULIDE CRS

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Added Modified

Molecular weight: 308.3098

Ref: 41-N0845000

Nimesulide

CAS: 51803-78-2

Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.

Formula: C₁₃H₁₂N₂O₅S

Purity: 98% - 99.91%

Color and Shape: Yellow Needle-Like Crystals

Molecular weight: 308.31

Ref: TM-T1133

Nimesulide

CAS: 51803-78-2

Nimesulide

Purity: 98%

Molecular weight: 308.31g/mol

Ref: 54-OR1030432

Nimesulide

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Purity: ≥ 98.0%

Color and Shape: White to yellow crystalline powder

Molecular weight: 308.31

Ref: 7W-GP5678

Nimesulide

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Yellow Solid

Molecular weight: 308.31

Ref: 4Z-N-084

Nimesulide

CAS: 51803-78-2

Nimesulide

Purity: ≥98%

Molecular weight: 308.31g/mol

Ref: 54-BUP11828

Nimesulide 100 µg/mL in Acetonitrile

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Single Solution

Molecular weight: 308.31

Ref: 04-A15526500AL-100

Nimesulide

Controlled Product

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Neat

Molecular weight: 308.31

Ref: 86-MM0378.00

Nimesulide

Controlled Product

CAS: 51803-78-2

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Neat

Molecular weight: 308.31

Ref: 04-C15526500

Nimesulide

CAS: 51803-78-2

Applications Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)

Formula: C₁₃H₁₂N₂O₅S

Color and Shape: Light Yellow

Molecular weight: 308.31

Ref: TR-N477500

Nimesulide - Bio-X ™

CAS: 51803-78-2

Nimesulide is a non-steroidal anti-inflammatory drug that is used to treat acute pain and primary dysmenorrhea. This drug is also a cyclooxygenase inhibitor and works by targeting a range of key mediators of the inflammatory process such as histamines and free radicals to reduce pain and inflammation.

Formula: C₁₃H₁₂N₂O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 308.31 g/mol

Ref: 3D-BN166246

Nimesulide

CAS: 51803-78-2

COX-2 inhibitor; nonsteroidal anti-inflammatory drug

Formula: C₁₃H₁₂N₂O₅S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 308.31 g/mol

Ref: 3D-FN26223

N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

CAS: 51803-78-2

M02164 - N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

Formula: C₁₃H₁₂N₂O₅S

Purity: 98%

Color and Shape: Powder

Molecular weight: 308.31

Ref: 10-M02164

Nimesulide

CAS: 51803-78-2

Color and Shape: Neat

Ref: 61-FOR0378.00