CAS 51818-85-0

(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Description:

The chemical substance with the name "(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid" and CAS number "51818-85-0" is a complex bicyclic compound that belongs to the class of thiazolidine derivatives. It features a bicyclic structure that includes a thiazolidine ring, which contributes to its unique chemical properties. The presence of multiple functional groups, such as an acetyloxy group and a phenylacetyl moiety, indicates potential for various biological activities, including antimicrobial properties. The stereochemistry of the compound is significant, as the specific configuration at the chiral centers can influence its pharmacological effects. This compound is often studied for its potential applications in medicinal chemistry, particularly in the development of antibiotics or other therapeutic agents. Its solubility, stability, and reactivity can vary based on the functional groups present, making it a subject of interest in both synthetic and medicinal chemistry research.

Formula: C₁₈H₁₈N₂O₇S

InChI: InChI=1/C18H18N2O7S/c1-9(21)27-7-11-8-28-17-12(16(24)20(17)13(11)18(25)26)19-15(23)14(22)10-5-3-2-4-6-10/h2-6,12,14,17,22H,7-8H2,1H3,(H,19,23)(H,25,26)

InChI key: InChIKey=CNAGMNMBHMQZPF-SUYBPPKGSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](O)C3=CC=CC=C3)=O)C2=O)(SCC1COC(C)=O)[H]

Synonyms:

• (6R,7R,2′R)-3-Acetoxymethyl-7-(2′-hydroxy-2′-phenylacetamido)ceph-3-em-4-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-hydroxyphenylacetyl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-, (6R,7R)-
• (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-(6alpha,7beta(R*)))-3-(Acetoxymethyl)-7-(hydroxyphenylacetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(hydroxyphenylacetyl)amino]-8-oxo-, [6R-[6α,7β(R*)]]-
• (6R,7R)-7α-[(R)-Hydroxyphenylacetylamino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid
• (7R)-3-[(Acetyloxy)methyl]-7-[[(R)-2-phenyl-2-hydroxyacetyl]amino]cepham-3-ene-4-carboxylic acid
• Cefamandole Impurity 24
• (7R)-3-(Acetyloxymethyl)-7-[[(R)-hydroxyphenylacetyl]amino]cepham-3-ene-4-carboxylic acid
• 7-[(D)-MANDELAMIDO]CEPHALOSPORANIC ACID

Cefamandole Impurity 24

CAS: 51818-85-0

Formula: C₁₈H₁₈N₂O₇S

Molecular weight: 406.41

Ref: 4Z-C-162031