CAS 51839-15-7

Dimethyl 5-iodosophthalate

Description:

Dimethyl 5-iodosophthalate, with the CAS number 51839-15-7, is an organic compound characterized by its structure, which includes a phthalate backbone substituted with two methyl ester groups and an iodine atom at the 5-position. This compound typically appears as a crystalline solid and is soluble in organic solvents such as dichloromethane and acetone, but has limited solubility in water. The presence of the iodine atom enhances its reactivity, making it useful in various chemical synthesis applications, particularly in the field of organic chemistry for the introduction of iodine into other molecules. Dimethyl 5-iodosophthalate can serve as an intermediate in the synthesis of more complex organic compounds, including pharmaceuticals and agrochemicals. Additionally, its derivatives may exhibit interesting biological activities, making it a subject of interest in medicinal chemistry. As with many chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its use.

Formula: C₁₀H₉IO₄

InChI: InChI=1/C10H9IO4/c1-14-9(12)6-3-7(10(13)15-2)5-8(11)4-6/h3-5H,1-2H3

SMILES: COC(=O)c1cc(cc(c1)I)C(=O)OC

Synonyms:

• Dimethyl 5-Iodobenzene-1,3-Dicarboxylate
• Dimethyl 5-Iodoisophthalate

Dimethyl 5-iodoisophthalate

CAS: 51839-15-7

Formula: C₁₀H₉IO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 320.0805

Ref: IN-DA0037Q4

Dimethyl 5-Iodoisophthalate

CAS: 51839-15-7

Dimethyl 5-Iodoisophthalate

Formula: C₁₀H₉IO₄

Purity: 98%

Molecular weight: 320.08

Ref: 54-OR1012931

Dimethyl 5-iodoisophthalate

CAS: 51839-15-7

Formula: C₁₀H₉IO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 320.082

Ref: 10-F018627

Dimethyl 5-Iodoisophthalate

Controlled Product

CAS: 51839-15-7

Applications Dimethyl 5-Iodoisophthalate is used for succinimidyl 3-iodobenzoate (SIB) with DOTA as prosthetic group for multi-modal labeling enhancing tumor uptake of radiolabelled monoclonal antibodies (mAbs).
References Vaidyanathan, G., et al.: Bioorg. Med. Chem., 20, 6929 (2012);

Formula: C₁₀H₉IO₄

Color and Shape: Neat

Molecular weight: 320.08

Ref: TR-D474180