CAS 51876-98-3

Gliamilide

Description:

Gliamilide, with the CAS number 51876-98-3, is a chemical compound that belongs to the class of sulfonamides. It is primarily recognized for its application in the pharmaceutical industry, particularly as an antidiabetic agent. Gliamilide functions by enhancing insulin sensitivity and promoting glucose uptake in peripheral tissues, making it beneficial for managing blood sugar levels in individuals with diabetes. The compound exhibits moderate solubility in water and is typically administered in oral form. Its chemical structure includes a sulfonamide group, which is characteristic of many drugs in this class, contributing to its biological activity. Additionally, gliamilide may have various side effects, which necessitate careful monitoring during treatment. As with many pharmaceuticals, its efficacy and safety profile are determined through clinical studies, and it is essential to adhere to prescribed dosages to minimize potential adverse reactions. Overall, gliamilide represents a significant therapeutic option in the management of diabetes, reflecting the ongoing efforts in medicinal chemistry to develop effective treatments for metabolic disorders.

Formula: C₂₃H₃₃N₅O₅S

InChI: InChI=1/C23H33N5O5S/c1-33-22-20(3-2-9-25-22)21(29)24-10-6-16-7-11-28(12-8-16)34(31,32)27-23(30)26-15-19-14-17-4-5-18(19)13-17/h2-5,9,16-19H,6-8,10-15H2,1H3,(H,24,29)(H2,26,27,30)/t17-,18+,19+/s2

InChI key: InChIKey=MQQJZPWSYVPWPF-FPICWYNDNA-N

SMILES: C(NC(NS(=O)(=O)N1CCC(CCNC(=O)C2=C(OC)N=CC=C2)CC1)=O)[C@@H]3[C@]4(C[C@@](C3)(C=C4)[H])[H]

Synonyms:

• 3-Pyridinecarboxamide, N-[2-[1-[[[[(bicyclo[2.2.1]hept-5-en-2-ylmethyl)amino]carbonyl]amino]sulfonyl]-4-piperidinyl]ethyl]-2-methoxy-, endo-
• 3-Pyridinecarboxamide, N-[2-[1-[[[[[(1R,2R,4R)-bicyclo[2.2.1]hept-5-en-2-ylmethyl]amino]carbonyl]amino]sulfonyl]-4-piperidinyl]ethyl]-2-methoxy-, rel-
• rel-N-[2-[1-[[[[[(1R,2R,4R)-Bicyclo[2.2.1]hept-5-en-2-ylmethyl]amino]carbonyl]amino]sulfonyl]-4-piperidinyl]ethyl]-2-methoxy-3-pyridinecarboxamide
• Gliamilide
• CP 27634

Gliamilide

CAS: 51876-98-3

Gliamilide is a high-potency sulfamylurea hypoglycemic agent.

Formula: C₂₃H₃₃N₅O₅S

Color and Shape: Solid

Molecular weight: 491.6

Ref: TM-T27415