CAS 5188-07-8

Sodium methanethiolate

Description:

Sodium methanethiolate, with the CAS number 5188-07-8, is an organosulfur compound that serves as a sodium salt of methanethiol. It is typically encountered as a white to off-white solid, which is highly soluble in water due to the presence of the sodium ion. This compound is characterized by its strong nucleophilic properties, making it useful in various organic synthesis reactions, particularly in the formation of thioethers and other sulfur-containing compounds. Sodium methanethiolate is also known for its ability to act as a reducing agent and can participate in reactions involving electrophiles. It has a distinct, pungent odor reminiscent of rotten cabbage, which is characteristic of methanethiol. Safety precautions are necessary when handling this compound, as it can be irritating to the skin, eyes, and respiratory system. Additionally, it should be stored in a cool, dry place, away from incompatible substances, to maintain its stability and reactivity.

Formula: CH₄S·Na

InChI: InChI=1S/CH4S.Na/c1-2;/h2H,1H3;

InChI key: InChIKey=XHXXWWGGXFUMAJ-UHFFFAOYSA-N

SMILES: CS.[Na]

Synonyms:

• (Methylsulfanyl)sodium
• Metanotiolato De Sodio
• Methanethiol, sodium salt (1:1)
• Methanethiolate de sodium
• Methyl mercaptan sodium salt
• Methylthiosodium
• Natriummethanthiolat
• Sodium Methanethiolate
• Sodium methanesulfenate
• Sodium methyl mercaptan
• Sodium methyl mercaptide
• Sodium methyl sulfide
• Sodium methylmercaptide
• Sodium methylthiolate
• Sodium thiomethoxide
• Sodium thiomethylate
• Sodium, (methylthio)-
• Thiomethoxide, Sodium

Methyl Mercaptan Sodium Salt (ca. 15% in Water)

CAS: 5188-07-8

Formula: CH₃NaS

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 70.08

Ref: 3B-M0096

Sodium methanethiolate

CAS: 5188-07-8

Sodium methanethiolate

Formula: ·CH₃S·Na

Purity: ≥95%

Color and Shape: white to off-white crystalline powder

Molecular weight: 70.08929g/mol

Ref: 54-OR28823

Sodium thiomethoxide

CAS: 5188-07-8

Formula: CH₃NaS

Color and Shape: White to yellow or brown powder or crystals

Molecular weight: 70.09

Ref: 7W-GK9372

Sodium thiomethoxide solution

CAS: 5188-07-8

Sodium thiomethoxide solution

Purity: ≥95%

Color and Shape: Liquid

Molecular weight: 70.08929g/mol

Ref: 54-OR55697

Sodium Methanethiolate (~20% in Water)

Controlled Product

CAS: 5188-07-8

Applications Strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.
E0
References Le Brazidec, J., et al.: J. Med. Chem., 47, 3865 (2004), Grem, J., et al.: J. Clin. Oncol., 23, 1885 (2005), Levason, W., et al.: Dalton Trans, 439 (2007),

Formula: CH₃S·Na

Color and Shape: Colourless

Molecular weight: 70.09

Ref: TR-S644800

Sodium Methanethiolate (95%)

Controlled Product

CAS: 5188-07-8

Formula: CH₃S·Na

Purity: 95%

Color and Shape: Neat

Molecular weight: 70.09

Ref: TR-S644805

Sodium methanethiolate

CAS: 5188-07-8

Methanethiol is a compound that occurs naturally in the environment. It is used as a fungicide, insecticide and herbicide. Methanethiol inhibits the growth of microorganisms by binding to metal ions on the surface of cells. This prevents DNA replication and protein synthesis, leading to cell death. Methanethiol also has anti-inflammatory properties which may be due to its ability to inhibit adenosine A1 receptor activity in humans.

Formula: CH₃NaS

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 70.09 g/mol

Ref: 3D-FS157170

3-Methyl-2-buten-1-thiol Preparation Kit

CAS: 39389-20-3, 5188-07-8, 5287-45-6

Stability Readily Oxidized
Applications A volatile aroma compound. We will provide a detailed procedure for the preparation of the thiol from the thiolacetate with spectral data upon request.
References Majcher, M., et al.: J. Agric. Food Chem., 55, 5754 (2007), Akiyama, M., et al.: Food Sci. Technol. Res., 15, 233 (2009), Breme, K., et al.: J. Agric. Food Chem., 57, 8572 (2009),

Formula: MixtureVisitourWebsite

Color and Shape: Colourless To Yellow

Molecular weight: Mixture - Visit our Website

Ref: TR-M294400

Sodium methanethiolate - 15% aqueous solution

CAS: 5188-07-8

Sodium methanethiolate is an antimicrobial agent that is a white, crystalline solid. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria. Sodium methanethiolate has been used for the treatment of infectious diseases, such as respiratory infections and skin infections, as well as autoimmune diseases and cardiovascular disorders. The oxidation catalyst in this compound may also have physiological effects on the body's cells and tissues.

Formula: CH₃NaS

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 70.09 g/mol

Ref: 3D-FS49739

Sodium thiomethoxide

CAS: 5188-07-8

Formula: CH₃NaS

Purity: %

Color and Shape: Solid

Molecular weight: 70.0893

Ref: IN-DA0039M2

Sodium Methanethiolate-13C

Controlled Product

CAS: 5188-07-8

Applications Sodium Methanethiolate-13C, is the labeled analogue of Sodium Methanethiolate (S644805), used as a nucleophile in organic synthesis. Sodium methanethiolate is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors.
References Bergman, A. & Wachtmeister, Chemosphere, 7, 949 (1978); Suzuki, T.,et al.: Bioorg. Med. Chem. Lett., 14, 3313 (2004)

Formula: CH₃NaS

Purity: >90%

Color and Shape: Neat

Molecular weight: 71.082

Ref: TR-S644807