CAS 51938-11-5

10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]-, hydrochloride (1:1)

Description:

10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]-, hydrochloride (1:1), with the CAS number 51938-11-5, is a chemical compound that belongs to the phenothiazine class, which is known for its diverse pharmacological properties. This substance features a phenothiazine core, characterized by a sulfur and nitrogen-containing heterocyclic structure, which contributes to its biological activity. The presence of a chloro substituent and a dimethylamino propyl side chain enhances its lipophilicity and potential interaction with biological targets, particularly in the central nervous system. As a hydrochloride salt, it is typically more soluble in water, facilitating its use in pharmaceutical formulations. The compound may exhibit antipsychotic, antihistaminic, or sedative effects, making it relevant in medicinal chemistry. Its specific characteristics, such as melting point, solubility, and stability, can vary based on formulation and environmental conditions. Safety and handling precautions are essential, as with all chemical substances, due to potential toxicity and side effects associated with phenothiazine derivatives.

Formula: C₁₇H₁₉ClN₂OS·ClH

InChI: InChI=1S/C17H19ClN2OS.ClH/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20;/h4-7,10-11,21H,3,8-9H2,1-2H3;1H

InChI key: InChIKey=OTIORHLXOLCOAV-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(SC=3C1=CC(Cl)=CC3)=CC(O)=CC2.Cl

Synonyms:

• 10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]-, monohydrochloride
• 7-Hydroxychlorpromazine hydrochloride
• 10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]-, hydrochloride (1:1)

7-Hydroxy Chlorpromazine Hydrochloride

CAS: 51938-11-5

Impurity Chlorpromazine 7-Hydroxy Impurity
Stability Hygroscopic
Applications 7-Hydroxychlorpromazine is the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);

Formula: C₁₇H₁₉ClN₂OS·HCl

Color and Shape: White To Light Purple

Molecular weight: 371.32

Ref: TR-H825065

7-Hydroxy chlorpromazine hydrochloride

CAS: 51938-11-5

Chlorpromazine is a cholinergic drug that is used to treat psychiatric patients. It has been shown to be effective in the treatment of schizophrenia and other psychotic disorders. Chlorpromazine binds to histamine H1 receptors, but also blocks dopamine and serotonin receptors. This drug has a long half-life in plasma (14.4 hours) and tissues, which may be due to its metabolites. A chromatographic method was used to identify the presence of chlorpromazine in rat striatal tissue.

Formula: C₁₇H₂₀Cl₂N₂OS

Purity: Min. 95%

Molecular weight: 371.32 g/mol

Ref: 3D-BCA93811