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CAS 51982-36-6

:

PGG2

Description:
PGG2, or Prostaglandin G2, is a chemical compound classified as a prostaglandin, which are lipid compounds derived from fatty acids and have diverse hormone-like effects in animals. It is primarily involved in various physiological processes, including inflammation, blood flow regulation, and the modulation of immune responses. PGG2 is characterized by its unstable nature, often rapidly converting to other prostaglandins, such as PGH2, through enzymatic reactions. This compound is typically synthesized in the body from arachidonic acid via the action of cyclooxygenase enzymes. PGG2 plays a crucial role in the biosynthesis of other prostaglandins and thromboxanes, which are important mediators in cardiovascular and inflammatory responses. Due to its biological significance, PGG2 is of interest in pharmacological research, particularly in the context of anti-inflammatory and analgesic drug development. However, its instability and rapid conversion to other forms can complicate its study and application in therapeutic contexts.
Formula:C20H32O6
InChI:InChI=1S/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
InChI key:InChIKey=SGUKUZOVHSFKPH-YNNPMVKQSA-N
SMILES:C(=C/[C@H](CCCCC)OO)\[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@]2(C[C@]1(OO2)[H])[H]
Synonyms:
  • Prostaglandin G2
  • PGG2
  • Endoperoxide G2
  • Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroperoxy-, (5Z,9α,11α,13E,15S)-
  • (5Z,9α,11α,13E,15S)-9,11-Epidioxy-15-hydroperoxyprosta-5,13-dien-1-oic acid
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Found 3 products.
  • Prostaglandin G2
    Glentham
    + Info

    Prostaglandin G2

    CAS:
    Formula:C20H32O6
    Molecular weight:368.46

    Ref: 7W-GL5834

    ne
    To inquire
  • Prostaglandin G2
    Larodan
    + Info

    Prostaglandin G2

    CAS:
    Formula:C20H32O6
    Purity:>95%
    Color and Shape:In solution, Acetone
    Molecular weight:368.47

    Ref: 48-12-2082

    500µg
    To inquire
  • Prostaglandin G2
    Targetmol
    + Info

    Prostaglandin G2

    CAS:
    <p>Prostaglandin G2 (PGG2) serves as the initial stable intermediate in the COX pathway, identifiable and characterizable due to its stability. This compound is identified as the C-15 hydroperoxide derivative of PGH2. Typically, PGG2 undergoes rapid metabolism via the inherent peroxidase activity of both COX-1 and COX-2 enzymes, resulting in the production of PGH2. PGH2 is crucial as it is the primary precursor for the generation of 2-series prostaglandins and thromboxanes.</p>
    Formula:C20H32O6
    Color and Shape:Solid
    Molecular weight:368.5

    Ref: TM-T84581