CAS 51987-99-6

N-(1,3,4-Thiadiazolyl)nicotinamide

CAS: 51987-99-6

Formula: C₈H₆N₄OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.2244

Ref: IN-DA00DDFN

TGN-020

CAS: 51987-99-6

TGN-020

Purity: ≥98%

Molecular weight: 206.22g/mol

Ref: 54-BUP13280

N-(1,3,4-Thiadiazol-2-Yl)Nicotinamide

CAS: 51987-99-6

N-(1,3,4-Thiadiazol-2-Yl)Nicotinamide

Purity: 99%

Molecular weight: 206.22g/mol

Ref: 54-OR1013937

TGN-020

CAS: 51987-99-6

TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.

Formula: C₈H₆N₄OS

Purity: 99.54% - 99.99%

Color and Shape: Solid

Molecular weight: 206.22

Ref: TM-T5102

N-(1,3,4-Thiadiazolyl)nicotinamide

Controlled Product

CAS: 51987-99-6

Applications A thiadiazole derivative as antitumor agent.
References Papadopoulos, M., et al.: J. Biol. Chem., 280, 13906 (2005), Gao, J., et al.: Anal. Biochem., 350, 165 (2006), Huber, V., et al.: Bioorg. Med. Chem., 17, 418 (2009),

Formula: C₈H₆N₄OS

Color and Shape: Off White Solid

Molecular weight: 206.22

Ref: TR-T344000

TGN-020

CAS: 51987-99-6

Purity: 98%

Molecular weight: 206.026

Ref: 10-F808546

N-(1,3,4-Thiadiazolyl)nicotinamide

CAS: 51987-99-6

N-(1,3,4-Thiadiazolyl)nicotinamide is an intracellular drug that inhibits the release of a growth factor, which may be involved in the development of migraine. It has been shown to inhibit the activity of the enzyme VEGF and reduces infarction volume in rats. N-(1,3,4-Thiadiazolyl)nicotinamide also has a neuroprotective effect by reducing reactive astrocytes and inhibiting fibrillary acidic protein expression in the cerebral cortex of rats. This drug is osmotically active and can induce neuronal damage due to brain swelling. N-(1,3,4-Thiadiazolyl)nicotinamide is also used as a stain for neurons in histological studies.

Formula: C₈H₆N₄OS

Purity: Min. 95%

Molecular weight: 206.22 g/mol

Ref: 3D-BCA98799