CAS 52-24-4: Thiotepa

Description: Thiotepa, with the CAS number 52-24-4, is a chemical compound classified as an alkylating agent, primarily used in chemotherapy for treating various cancers. It is a colorless to pale yellow liquid that is soluble in water and organic solvents. The molecular structure of thiotepa includes a nitrogen atom and a sulfur atom, which contribute to its reactivity. As an alkylating agent, thiotepa works by forming covalent bonds with DNA, leading to cross-linking and ultimately inhibiting cell division, which is particularly effective against rapidly dividing cancer cells. Its use is associated with a range of side effects, including myelosuppression, which can lead to decreased blood cell counts, and other toxicities affecting various organ systems. Due to its potent effects and potential for toxicity, thiotepa is typically administered under strict medical supervision. Safety precautions are essential when handling thiotepa, as it is considered hazardous. Overall, thiotepa plays a significant role in oncology, particularly in combination therapies for certain malignancies.

Formula: C₆H₁₂N₃PS

InChI: InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

InChI key: InChIKey=FOCVUCIESVLUNU-UHFFFAOYSA-N

SMILES: S=P(N1CC1)(N2CC2)N3CC3

Synonyms:

• 1,1',1''-Phosphinothioylidynetrisaziridine
• 1,1′,1′′-Phosphinothioylidynetris[aziridine]
• Ai 3-24916
• Aziridine, 1,1′,1′′-phosphinothioylidynetris-
• Cbc 806495
• Girostan
• N,N',N''-Triethylenethiophosphoramide
• N,N',N''-Triethylenethiophosphortriamide
• Nci C01649
• Nsc 6396
• Oncotepa
• Oncothio-tepa
• Oncotiotepa
• Phosphine sulfide, tris(1-aziridinyl)-
• Phosphorothioic acid triethylenetriamide
• Phosphorothioic triamide, N,N',N''-tri-1,2-ethanediyl-
• Sk 6882
• Stepa
• Tepadina
• Tespa
• Tespamin
• Tespamine
• Thio-Tep
• Thio-Tepa S
• Thiofozil
• Thiophosphamide
• Thiophosphoramide, N,N',N''-tri-1,2-ethanediyl-
• Thioplex
• Thiotef
• Thiotepa
• Thiotriethylenephosphoramide
• Tio-TEF
• Tiofosfamid
• Tiofosyl
• Tiofozil
• Tiotepa
• Tri(ethyleneimino)thiophosphoramide
• Tri-1-aziridinylphosphine sulfide
• Triaziridinylphosphine sulfide
• Triaziridinylphosphinesulfide
• Triethylenethiophosphoramide
• Triethylenethiophosphorotriamide
• Tris(1-aziridinyl)phosphine sulfide
• Tris(aziridinyl)phosphine sulfide
• Tris(aziridinyl)phosphine-thioxide
• Tris-(1-Aziridinyl)-Phosphin-Sulfid
• Tspa

Thiotepa

CAS: 52-24-4

• Formula: C₆H₁₂N₃PS
• Purity: 98.7%
• Color and Shape: White Solid
• Molecular weight: 189.04896

Thiotepa

CAS: 52-24-4

Heterocyclic compounds with nitrogen hetero-atom(s) only, excluding aromatic or modified aromatic

• Formula: C₆H₁₂N₃PS
• Color and Shape: White Flakes
• Molecular weight: 189.04896

Thio-TEPA

CAS: 52-24-4

Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.

• Formula: C₆H₁₂N₃PS
• Purity: 98.45% - 99.07%
• Color and Shape: White Crystals Or Powder
• Molecular weight: 189.22

Thio-TEPA

CAS: 52-24-4

• Purity: 98.45%
• Molecular weight: 189.22g/mol

Thio-TEPA

CAS: 52-24-4

• Formula: C₆H₁₂N₃PS
• Purity: ≥ 98.0%
• Color and Shape: White crystalline powder
• Molecular weight: 189.22

Thiotepa

CAS: 52-24-4

• Formula: C₆H₁₂N₃PS
• Molecular weight: 189.22

Thiotepa

CAS: 52-24-4

• Formula: C₆H₁₂N₃PS
• Purity: >95.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 189.22

Triethylenethiophosphoramide

CAS: 52-24-4

Applications This substance is listed as a known human carcinogen. It is useful for the …

• Formula: C₆H₁₂N₃PS
• Color and Shape: Neat
• Molecular weight: 189.22

Thiotepa

CAS: 52-24-4

Please enquire for more information about Thiotepa including the price, delivery time and more detailed …

• Formula: C₆H₁₂N₃PS
• Purity: (31P-Nmr) Min. 95%
• Color and Shape: Powder
• Molecular weight: 189.22 g/mol