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CAS 52-28-8

:

(-)-Codeine phosphate

Description:
(-)-Codeine phosphate, with the CAS number 52-28-8, is an opiate used primarily for its analgesic and antitussive properties. It is a naturally occurring alkaloid derived from the opium poppy, Papaver somniferum, and is chemically classified as a phenanthrene derivative. This compound is characterized by its ability to bind to opioid receptors in the central nervous system, leading to pain relief and suppression of cough reflexes. (-)-Codeine phosphate is typically administered in its phosphate salt form to enhance solubility and bioavailability. It exhibits moderate potency compared to other opioids, such as morphine, and is often used in combination with other medications for enhanced therapeutic effects. The substance is known for its potential for dependence and abuse, necessitating careful regulation and monitoring in clinical use. Additionally, it can cause side effects such as drowsiness, constipation, and respiratory depression, particularly at higher doses or in sensitive individuals. As with all opioids, its use should be carefully managed to mitigate risks associated with addiction and overdose.
Formula:C18H21NO3·H3O4P
InChI:InChI=1S/C18H21NO3.H3O4P/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-5(2,3)4/h3-6,11-13,17,20H,7-9H2,1-2H3;(H3,1,2,3,4)/t11-,12+,13-,17-,18-;/m0./s1
InChI key:InChIKey=WUXLCJZUUHIXFY-FFHNEAJVSA-N
SMILES:P(=O)(O)(O)O.O[C@@H]1[C@]2([C@]34C=5C(O2)=C(OC)C=CC5C[C@]([C@@]3(C=C1)[H])(N(C)CC4)[H])[H]
Synonyms:
  • (-)-Codeine phosphate
  • Codeine Phosphate [D.D]
  • Codeine phosphate (1:1)
  • Galcodine
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-, phosphate (1:1)
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-, phosphate (1:1) (salt)
  • Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methyl-, phosphate (1:1) (salt)
  • Tricodein
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Found 2 products.
  • Codeine Phosphate (1 mg/ml in Methanol)
    TRC
    + Info

    Codeine Phosphate (1 mg/ml in Methanol)

    Controlled Product
    CAS:
    Formula:C18H21NO3·H3O4P
    Color and Shape:Single Solution
    Molecular weight:397.36

    Ref: TR-KIT2460

    1x1ml
    1,008.00€
  • Codeine Phosphate
    TRC
    + Info

    Codeine Phosphate

    Controlled Product
    CAS:

    Applications Present in opium from 0.7% to 2.5%, depending on the source. Weak narcotic analgesic, perhaps due to conversion to morphine, with minimal hypnotic properties; potent antitussive.Controlled substance (opiate).
    Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
    References Eddy, S., et al.: J. Pharmacol. Exp. Ther., 67, 127 (1939), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 10, 93 (1981),

    Formula:C18H21NO3·H3O4P
    Color and Shape:Neat
    Molecular weight:397.36

    Ref: TR-C634080

    1g
    3,140.00€
    250mg
    1,549.00€