CAS 52-31-3

Cyclobarbital

Description:

Cyclobarbital is a barbiturate derivative that exhibits sedative and hypnotic properties. It is characterized by its cyclic structure, which includes a barbituric acid core modified with a cyclobutyl group. This compound is typically used in the medical field for its ability to induce sleep and manage anxiety, although its use has declined due to the potential for dependence and the availability of safer alternatives. Cyclobarbital acts primarily as a central nervous system depressant, enhancing the effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor, which leads to increased inhibitory neurotransmission. The substance is generally administered in oral form and has a relatively short duration of action. Its pharmacokinetics can be influenced by various factors, including metabolic pathways and individual patient characteristics. As with other barbiturates, caution is advised due to the risk of overdose and interactions with other medications. Overall, while cyclobarbital has therapeutic applications, its use must be carefully monitored in clinical settings.

Formula: C₁₂H₁₆N₂O₃

InChI: InChI=1S/C12H16N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h6H,2-5,7H2,1H3,(H2,13,14,15,16,17)

InChI key: InChIKey=WTYGAUXICFETTC-UHFFFAOYSA-N

SMILES: C(C)C1(C(=O)NC(=O)NC1=O)C=2CCCCC2

Synonyms:

• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-5-ethyl-
• 5-(1-Cyclohexen-1-yl)-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• 5-(1-Cyclohexen-1-yl)-5-ethylbarbituric acid
• 5-(1-Cyclohexenyl)-5-ethylbarbituric acid
• 5-(Cyclohex-1-Enyl)-5-Ethylbarturic Acid
• 5-Ethyl-5-(1-cyclohexenyl)barbituric acid
• Adorm
• Amnosed
• Barbituric acid, 5-(1-cyclohexen-1-yl)-5-ethyl-
• Cavonyl
• Cyclobarbitone
• Cyclodorm
• Cyclohexal
• Ethylhexabital
• Fanodorm
• Fanodormo
• Hexadorm
• Hexemal
• Hypnoval
• Irifan
• Namuron
• Palinum
• Phanodorm
• Phanotal
• Philodorm
• Praelumin
• Pralumin
• Pro-Sonil
• Sonaform
• Sonoform

Cyclobarbital

Controlled Product

CAS: 52-31-3

Applications Cyclobarbital has been used as an anesthetic and sedative. Controlled substance (depressant).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hofrichter, G., et al.: Arzneim.-Forsch., 17, 242 (1967),

Formula: C₁₂H₁₆N₂O₃

Color and Shape: Neat

Molecular weight: 236.27

Ref: TR-C987775