CAS 52-66-4

(±)-Penicillamine

Description:

(±)-Penicillamine is a chelating agent and a derivative of penicillin, primarily used in the treatment of conditions such as rheumatoid arthritis and Wilson's disease. It is an amino acid with a thiol group, which allows it to form complexes with heavy metals, facilitating their excretion from the body. The substance exists as a racemic mixture, meaning it contains equal parts of two enantiomers, which can exhibit different biological activities. (±)-Penicillamine is typically administered orally and is known for its ability to reduce inflammation and modulate immune responses. Its chemical structure includes a carboxylic acid group, an amine group, and a thiol group, contributing to its reactivity and therapeutic properties. Common side effects may include gastrointestinal disturbances, skin rashes, and, in rare cases, more severe reactions such as nephrotoxicity. Due to its complex interactions and potential for adverse effects, careful monitoring is essential during treatment. Overall, (±)-Penicillamine plays a significant role in managing specific medical conditions, particularly those involving metal accumulation in the body.

Formula: C₅H₁₁NO₂S

InChI: InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)

InChI key: InChIKey=VVNCNSJFMMFHPL-UHFFFAOYSA-N

SMILES: C(C(C)(C)S)(C(O)=O)N

Synonyms:

• 2-Amino-3-mercapto-3-methylbutanoic acid
• 2-Amino-3-mercapto-3-methylbutyric acid
• 2-Amino-3-methyl-3-sulfanylbutanoic acid
• 2-Azaniumyl-3-methyl-3-sulfanylbutanoate
• 3,3-Dimethyl-DL-cysteine
• 3,3-Dimethyl-DL-cysteine~3-Mercapto-DL-valine
• 3-Mercaptovaline
• <span class="text-smallcaps">DL</span>-3-Mercaptovaline
• <span class="text-smallcaps">DL</span>-Penicillamine
• <span class="text-smallcaps">DL</span>-Valine, 3-mercapto-
• <span class="text-smallcaps">DL</span>-β-Mercaptovaline
• Cysteine, 3,3-dimethyl-
• DL-beta-mercaptovaline
• NSC 22880
• NSC 44656
• Penicillamine
• Valine, 3-mercapto-
• Valine, 3-mercapto-, <span class="text-smallcaps">DL</span>-
• dl-DMC
• β,β-Dimethylcysteine
• β-Mercaptovaline
• β-Thiovaline
• DL-Valine, 3-mercapto-

DL-Penicillamine, 97+%

CAS: 52-66-4

Heavy metal chelating agentDL-Penicillamine is used as an antirheumatic. It also serves as a chelating agent for heavy metals. Further, it is used in the treatment of Wilson's desease, Cystinuria, Scleroderma and arsenic poisoning. This Thermo Scientific Chemicals brand product was originally part o

Formula: C₅H₁₁NO₂S

Purity: 97+%

Color and Shape: Powder, White

Molecular weight: 149.21

Ref: 02-B24710

DL-Penicillamine

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.2113

Ref: IN-DA00DENL

DL-Penicillamine

CAS: 52-66-4

DL-Penicillamine treats Wilson's disease and rheumatoid arthritis, chelates copper, reduces cystine excretion, and affects T-cell activity.

Formula: C₅H₁₁NO₂S

Purity: 99.79% - ≥95%

Color and Shape: Fine White Or Practically White Crystalline Powder Solid

Molecular weight: 149.21

Ref: TM-T0983L

DL-Penicillamine

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 149.21

Ref: 7W-GM3750

2-Amino-3-Mercapto-3-Methylbutanoic Acid

CAS: 52-66-4

2-Amino-3-Mercapto-3-Methylbutanoic Acid

Purity: 96%

Molecular weight: 149.21g/mol

Ref: 54-OR1028887

DL-Penicillamine

CAS: 52-66-4

DL-Penicillamine

Purity: ≥95%

Molecular weight: 149.21g/mol

Ref: 54-BUP11111

DL-Penicillamine

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Molecular weight: 149.21

Ref: 4Z-P-8918

DL-Penicillamine

Controlled Product

CAS: 52-66-4

Applications DL-Penicillamine is a penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010); Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010)

Formula: C₅H₁₁NO₂S

Color and Shape: Neat

Molecular weight: 149.21

Ref: TR-P223010

DL-Penicillamine

CAS: 52-66-4

DL-Penicillamine is a penicillamine that is used in the treatment of various diseases such as rheumatoid arthritis and primary sclerosing cholangitis. It has been shown to inhibit the production of inflammatory prostaglandins, which are responsible for pain and swelling. DL-Penicillamine has been used as a fluorescence probe for the detection of nonsteroidal anti-inflammatory drugs in water samples. DL-Penicillamine is also used to study coordination geometry and rate constants in solid tumours using fluorescence spectroscopy. This drug can be analyzed using chromatographic techniques or by X-ray diffraction data obtained with an electrochemical impedance spectroscopy system. The analytical method was published in 1981 by J.D. Hamer, et al., in "Analytical Chemistry".

Formula: C₅H₁₁NO₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 149.21 g/mol

Ref: 3D-FP30177

2-Amino-3-mercapto-3-methylbutanoic acid

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Purity: 95%

Color and Shape: Solid, White crystalline powder

Molecular weight: 149.21

Ref: 10-F239459

Bacampicillin EP Impurity F

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Molecular weight: 149.2

Ref: ST-EA-CP-B105004

DL-Penicillamine

CAS: 52-66-4

Formula: C₅H₁₁NO₂S

Molecular weight: 149.21

Ref: ST-EA-CP-P45026