CAS 52-86-8: Haloperidol

Description:Haloperidol is an antipsychotic medication primarily used to treat schizophrenia, acute psychosis, and for the management of Tourette syndrome. It belongs to the butyrophenone class of drugs and functions as a dopamine antagonist, particularly blocking D2 receptors in the brain, which helps alleviate symptoms of psychosis. Haloperidol is typically administered in oral or injectable forms and is known for its relatively long half-life, allowing for once-daily dosing in many cases. The substance appears as a white to off-white crystalline powder and is sparingly soluble in water, but more soluble in organic solvents like ethanol and chloroform. Common side effects include sedation, extrapyramidal symptoms, and potential tardive dyskinesia with long-term use. Due to its potency, careful monitoring is essential to manage dosage and mitigate adverse effects. Haloperidol is also sometimes used off-label for various behavioral disorders and as an adjunct in severe agitation or delirium.

Formula:C₂₁H₂₃ClFNO₂

InChI:InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

InChI key:InChIKey=LNEPOXFFQSENCJ-UHFFFAOYSA-N

SMILES:O=C(C1=CC=C(F)C=C1)CCCN2CCC(O)(C3=CC=C(Cl)C=C3)CC2

Synonyms:
1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine
1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-
4-(4-Chlorophenyl)-1-[4-(4-Fluorophenyl)-4-Oxobutyl]-4-Hydroxypiperidinium
4-(4-Hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
4-[4-(p-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
Aloperidin
Bioperidolo
Brotopon
Butyrophenone, 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluoro-
See more synonyms
Dozic
Einalon S
Eukystol
Haldol
Haloperin
Halosten
Keselan
Linton
McN-JR 1625
Neurodol
Nsc 170973
Nsc 615296
Peluces
R 1625
Serenace
Serenase
Serenelfi
Sigaperidol
γ-[4-(p-Chlorphenyl)-4-hydroxypiperidino]-p-fluorbutyrophenone

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Product data	Purity	Price range	Estimated delivery
Haloperidol REF: 02-J61688CAS: 52-86-8	- - -	To inquire	Wed 23 Apr 25
Haloperidol REF: 47-407CAS: 52-86-8	99.8%	242.00 €	Tue 29 Apr 25
Haloperidol for peak identification CRS REF: 41-Y0001518CAS: 52-86-8	- - -	115.00 €	Tue 29 Apr 25
Haloperidol for system suitability CRS REF: 41-Y0001517CAS: 52-86-8	- - -	115.00 €	Tue 29 Apr 25
Haloperidol CRS REF: 41-H0100000CAS: 52-86-8	- - -	115.00 €	Tue 29 Apr 25
Haloperidol RS REF: 41-ICRS0323CAS: 52-86-8	- - -	102.00 €	Tue 29 Apr 25
Haloperidol REF: 45-1303002CAS: 52-86-8	- - -	463.00 €	Mon 28 Apr 25
Haloperidol REF: TM-T0025CAS: 52-86-8	98.69% - 98.97%	35.00 €~71.00 €	Tue 29 Apr 25
Haloperidol REF: 54-PC109208CAS: 52-86-8	98%	32.00 €~2,001.00 €	Wed 30 Apr 25
Haloperidol REF: 54-BUP11764CAS: 52-86-8	≥98%	52.00 €~107.00 €	Wed 30 Apr 25
Haloperidol (Haloperidol Decanoate EP Impurity G) REF: 4Z-H-011CAS: 52-86-8	- - -	224.00 €~971.00 €	Wed 30 Apr 25
Haloperidol REF: 7W-GP6431CAS: 52-86-8	- - -	To inquire	Wed 30 Apr 25
Haloperidol Decanoate N-Oxide (trans-Isomer) REF: 4Z-H-0117CAS: 52-86-8	- - -	406.00 €~2,848.00 €	Wed 30 Apr 25
Haloperidol REF: 04-C14059400CAS: 52-86-8	- - -	110.00 €	Fri 02 May 25
Haloperidol REF: 86-MM1165.00CAS: 52-86-8	- - -	1,302.00 €	Fri 02 May 25
Haloperidol REF: 3B-H0912CAS: 52-86-8	>98.0%(T)(HPLC)	84.00 €~273.00 €	Fri 02 May 25
Haloperidol REF: 10-M04089CAS: 52-86-8	99%	To inquire	Fri 09 May 25
Haloperidol REF: TR-H103700CAS: 52-86-8	- - -	116.00 €~219.00 €	Fri 09 May 25
Haloperidol REF: 3D-FH23734CAS: 52-86-8	Min. 95%	143.00 €~1,324.00 €	Mon 12 May 25
Haloperidol - Bio-X ™ REF: 3D-BH166165CAS: 52-86-8	Min. 95%	147.00 €	Mon 12 May 25