CAS 52-88-0

Atropine methyl nitrate

Description:

Atropine methyl nitrate, with the CAS number 52-88-0, is a chemical compound derived from atropine, a tropane alkaloid. It is characterized by its structure, which includes a methyl nitrate group attached to the atropine molecule. This compound is typically a white to off-white crystalline solid and is soluble in water and organic solvents. Atropine methyl nitrate exhibits pharmacological properties similar to those of atropine, acting as an anticholinergic agent that can inhibit the action of acetylcholine at muscarinic receptors. It is primarily used in research settings and has potential applications in medicine, particularly in the treatment of certain types of poisoning and as a pre-anesthetic medication. However, due to its potent effects, it must be handled with care, and its use is regulated. Safety data sheets should be consulted for information on toxicity, handling, and storage to ensure safe usage in laboratory or clinical environments.

Formula: C₁₈H₂₆NO₃·NO₃

InChI: InChI=1/C18H26NO3.NO3/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13;2-1(3)4/h3-7,14-17,20H,8-12H2,1-2H3;/q+1;-1/t14-,15+,16+,17?;

InChI key: InChIKey=NEDVJZNVOSNSHF-KUMOIWDRNA-N

SMILES: C[N+]1(C)[C@]2(C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].N(=O)(=O)[O-]

Synonyms:

• 3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane nitrate
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, (3-endo)-, nitrate (salt)
• atropine methonitrate
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, (3-endo)-, nitrate (1:1)
• Methylatropine nitrate
• 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, nitrate, (±)-tropate (ester)
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, endo-(±)-, nitrate (salt)
• 8-Methylatropinium nitrate

Methylatropine (nitrate)

CAS: 52-88-0

Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.

Formula: C₁₈H₂₆N₂O₆

Color and Shape: Solid

Molecular weight: 366.414

Ref: TM-T36204