CAS 520-27-4: Diosmin

Description: Diosmin is a flavonoid compound primarily derived from citrus fruits, particularly oranges and lemons. It is classified as a glycoside, specifically a flavone glycoside, which means it consists of a flavonoid moiety linked to a sugar molecule. Diosmin is known for its potential health benefits, particularly in the treatment of venous insufficiency and related conditions, as it may improve venous tone and reduce capillary permeability. Its chemical structure includes a chromone ring, which is characteristic of flavonoids, and it exhibits antioxidant properties. Diosmin is often used in dietary supplements and pharmaceutical formulations, and it is generally well-tolerated, although some individuals may experience mild gastrointestinal side effects. The compound is soluble in water and organic solvents, making it versatile for various applications. Additionally, diosmin is often studied for its anti-inflammatory and protective effects on blood vessels, contributing to its use in managing conditions like hemorrhoids and varicose veins.

Formula: C₂₈H₃₂O₁₅

InChI: InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

InChI key: InChIKey=GZSOSUNBTXMUFQ-YFAPSIMESA-N

SMILES: O=C1C=C(OC2=CC(OC3OC(COC4OC(C)C(O)C(O)C4O)C(O)C(O)C3O)=CC(O)=C12)C=5C=CC(OC)=C(O)C5

Synonyms:

• 3',5,7-Trihydroxy-4'-Methoxyflavone 7-Rutinoside
• 3,5,7-Trihydroxy-4-methoxyflavone-7- rutinoside
• 3′,5,7-Trihydroxy-4′-methoxyflavone 7-O-rutinoside
• 3′,5-Dihydroxyl-4′-methoxylflavanone-7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnosyl (1→6)-β-<smallcap>D</span>-glucopyranoside
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-
• 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-D-mannopyranosyl)-beta-D-glucopyranoside
• 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
• 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside
• 7-[[6-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
• Barosmin
• Buchu resin
• Diosmetin 7-O-rhamnosyl(1→6)-glucoside
• Diosmetin 7-O-rutinoside
• Diosmetin 7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→6)-β-<smallcap>D</span>-glucopyranoside
• Diosmetin 7-rutinoside
• Diosmetin 7-β-rutinoside
• Diosmil
• Diosmine
• Diosven
• Dioven
• Diovenor
• Flebodia
• Flebosmil
• Flebosten
• Hemerven
• Insuven
• Litosmil
• Phlebodia
• Tovene
• Varinon
• Ven-Detrex
• Venex 500
• Venosmine
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-
• Diosmin
• 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Diosmin

CAS: 520-27-4

Diosmin exhibits anti-proliferative and anti-inflammatory. It is used in the treatment of venous disease, i.e., …

• Formula: C₂₈H₃₂O₁₅
• Molecular weight: 608.5

Diosmin

CAS: 520-27-4

Diosmin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

• Formula: C₂₈H₃₂O₁₅
• Purity: (HPLC) ≥99%
• Color and Shape: Powder
• Molecular weight: 608.56

Diosmin CRS

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Molecular weight: 608.5447

Diosmin for system suitability CRS

CAS: 520-27-4

Diosmin for Shepherd's purse CRS

CAS: 520-27-4

Diosmin

CAS: 520-27-4

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

• Formula: C₂₈H₃₂O₁₅
• Color and Shape: Light Grey Powder
• Molecular weight: 608.17412

4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 608.5447

Diosmin

CAS: 520-27-4

Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.

• Formula: C₂₈H₃₂O₁₅
• Purity: 97.90%
• Color and Shape: Greyish-Yellow Or Light Yellow Hygroscopic Powder
• Molecular weight: 608.54

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Color and Shape: Brown Solid
• Molecular weight: 608.55

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Purity: ≥ 90.0% (anhydrous basis)
• Color and Shape: Yellow to green-yellow or yellow-brown powder
• Molecular weight: 608.50

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Color and Shape: Neat
• Molecular weight: 608.54

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Purity: 95%~99%
• Molecular weight: 608.549

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Purity: >85.0%(HPLC)
• Color and Shape: White to Gray to Brown powder to crystal
• Molecular weight: 608.55

Diosmin

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₅
• Purity: By hplc: 99.86% (Typical Value in Batch COA)
• Color and Shape: yellow solid
• Molecular weight: 608.54g/mol

Diosmin

CAS: 520-27-4

Natural glycoside

• Formula: C₂₈H₃₂O₁₅
• Purity: ≥ 90.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 608.55

Diosmin

CAS: 520-27-4

Applications Naturally occurring flavonic glycoside; rhamnoglycoside of Diosmetin. Capillary protectant. References Damon, M., et al.: …

• Formula: C₂₈H₃₂O₁₅
• Color and Shape: Neat
• Molecular weight: 608.54

Diosmin - 90%

CAS: 520-27-4

Phlebotropic drug used in the treatment of venous disease

• Formula: C₂₈H₃₂O₁₅
• Purity: Min. 95%
• Color and Shape: Yellow Powder
• Molecular weight: 608.54 g/mol

Diosmin Oxireno Derivative

CAS: 520-27-4

• Formula: C₂₈H₃₂O₁₆
• Color and Shape: Neat
• Molecular weight: 624.544

Diosmin-d3

CAS: 520-27-4

• Formula: C₂₈D₃H₂₉O₁₅
• Color and Shape: Neat
• Molecular weight: 611.563