CAS 520-36-5

Apigenin

Description:

Apigenin is a naturally occurring flavonoid found in various plants, particularly in fruits, vegetables, and herbs such as parsley, chamomile, and celery. Its chemical formula is C15H10O5, and it features a flavone structure characterized by a chromone backbone with hydroxyl groups at specific positions. Apigenin is known for its potential health benefits, including anti-inflammatory, antioxidant, and anticancer properties. It exhibits a yellow crystalline appearance and is soluble in organic solvents like ethanol and dimethyl sulfoxide, but has limited solubility in water. Apigenin interacts with various biological pathways, influencing cell signaling and gene expression, which contributes to its therapeutic potential. Additionally, it has been studied for its effects on anxiety and sleep, making it a subject of interest in both nutritional and pharmaceutical research. Its safety profile is generally favorable, but further studies are needed to fully understand its mechanisms and efficacy in clinical applications.

Formula: C₁₅H₁₀O₅

InChI: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H

InChI key: InChIKey=KZNIFHPLKGYRTM-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1)C3=CC=C(O)C=C3)=CC(O)=CC2O

Synonyms:

• 4',5,7-Trihydroxyflavone
• 4′,5,7-Trihydroxyflavone
• 5,7,4'-Trihydroxyflavone
• 5,7-Dihidroxi-2-(4-Hidroxifenil)-4-Benzopirona
• 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Benzopyrone
• 5,7-Dihydroxy-2-(4-Hydroxyphenyl)chromen-4-one
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 5,7-Dihydroxy-2-p-hydroxyphenyl-4-chromenone
• Apegenin
• Apigenin
• Apigenine
• Apigenol
• Chamomile
• Flavone, 4',5,7-trihydroxy-
• Flavone, 4′,5,7-trihydroxy-
• Ly 080400
• Nsc 83244
• Pelargidenon 1449
• St 056301
• Uccf 031
• Versulin
• 75580
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
• C.I. Natural Yellow 1

Apigenin

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 270.24

Ref: 3B-A1514

Apigenin

CAS: 520-36-5

Apigenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₁₀O₅

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 270.25

Ref: 11-1102S

Apigenin (5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone)

CAS: 520-36-5

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₁₅H₁₀O₅

Color and Shape: Off-White Light Brown Yellow Powder

Molecular weight: 270.05282

Ref: 45-1040683

Apigenin

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 270.2369

Ref: IN-DA0034H3

Apigenin

CAS: 520-36-5

Apigenin

Formula: C₁₅H₁₀O₅

Purity: 97%

Color and Shape: light beige solid

Molecular weight: 270.24g/mol

Ref: 54-BIK9018

Apigenin

CAS: 520-36-5

Apigenin

Purity: ≥95%

Molecular weight: 270.24g/mol

Ref: 54-BUP17818

Apigenin

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Purity: ≥ 98.0% (anhydrous basis)

Color and Shape: Yellow or brown powder

Molecular weight: 270.24

Ref: 7W-GP1532

Apigenin

CAS: 520-36-5

Apigenin, a naturally occurring plant flavone (4', 5, 7,-trihydroxyflavone) abundantly present in common fruits and vegetables including parsley, onions, oranges, tea, chamomile, wheat sprouts and some seasonings, has been shown to possess remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties.

Formula: C₁₅H₁₀O₅

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 270.24

Ref: BP-BP0177

Apigenin 100 µg/mL in Acetonitrile:Methanol

Controlled Product

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Color and Shape: Single Solution

Molecular weight: 270.24

Ref: 04-A10290600MC-100

Apigenin

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Color and Shape: Neat

Molecular weight: 270.24

Ref: 04-C10290600

Apigenin

CAS: 520-36-5

Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.

Formula: C₁₅H₁₀O₅

Purity: 97.64% - 99.66%

Color and Shape: Yellow Needles From Aqueous Pyridine Solid

Molecular weight: 270.24

Ref: TM-T2175

Apigenin

CAS: 520-36-5

Formula: C₁₅H₁₀O₅

Molecular weight: 270.24

Ref: 4Z-A-746

Apigenin

CAS: 520-36-5

Apigenin

Formula: C₁₅H₁₀O₅

Purity: 97%

Color and Shape: faint beige powder

Molecular weight: 270.24g/mol

Ref: 54-OR7265T

Apigenin

CAS: 520-36-5

Oxygen-heterocyclic compound

Formula: C₁₅H₁₀O₅

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 270.24

Ref: 5G-89159

Apigenin

Controlled Product

CAS: 520-36-5

Applications Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.uv(max)ethanol: 269, 340 nm (e= 18,800, 20,900) moderately sol. in hot alcohol
References Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994); Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994); Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995);

Formula: C₁₅H₁₀O₅

Color and Shape: Yellow To Brown

Molecular weight: 270.24

Ref: TR-A726500

4,5,7-Trihydroxyflavone

CAS: 520-36-5

M01289 - 4,5,7-Trihydroxyflavone

Formula: C₁₅H₁₀O₅

Purity: 95%

Color and Shape: Solid, Light yellow powder

Molecular weight: 270.24

Ref: 10-M01289

Apigenin - 97%

CAS: 520-36-5

Apigenin - 97% is a high-purity flavonoid compound, which is primarily derived from various plant sources such as parsley, chamomile, and celery. This compound is known for its significant presence in the plant kingdom, where it functions as a secondary metabolite contributing to plant defense.

Formula: C₁₅H₁₀O₅

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 270.24 g/mol

Ref: 3D-FA16099

Apigenin - 94%

CAS: 520-36-5

Apigenin - 94% is a purified form of apigenin, which is a naturally occurring flavonoid. It is primarily sourced from various plant species, including parsley, celery, and chamomile, where it is a prominent active component. The mode of action of apigenin involves multiple biochemical pathways: it acts as an anti-inflammatory agent, modulates enzyme activities, and exhibits antioxidant properties by scavenging free radicals. Additionally, apigenin interacts with cellular signaling pathways, such as the MAPK and PI3K/Akt, which contribute to its protective effects against oxidative stress and its potential in promoting apoptosis in cancerous cells.

Formula: C₁₅H₁₀O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 270.24 g/mol

Ref: 3D-FA159894

4',5,7-Trihydroxyflavone, 97%

CAS: 520-36-5

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. This Thermo Scientif

Formula: C₁₅H₁₀O₅

Purity: 97%

Color and Shape: Cream to yellow to brown, Powder

Molecular weight: 270.24

Ref: 02-L15041