CAS 520-85-4

Medroxyprogesterone

Description:

Medroxyprogesterone is a synthetic progestin, a type of hormone that mimics the effects of natural progesterone. It is primarily used in various medical applications, including hormone replacement therapy, contraception, and the treatment of certain menstrual disorders. Medroxyprogesterone is characterized by its ability to regulate ovulation and menstruation, making it effective in managing conditions like endometriosis and abnormal uterine bleeding. The substance is typically administered in oral or injectable forms, with the injectable form often providing prolonged effects. Chemically, it is a derivative of 17α-hydroxyprogesterone and features a modified steroid structure that enhances its stability and bioavailability. Medroxyprogesterone acts by binding to progesterone receptors, influencing gene expression and cellular activity in target tissues. Its pharmacokinetics include a relatively long half-life, allowing for less frequent dosing in clinical settings. As with any medication, it may have side effects, and its use should be monitored by healthcare professionals to ensure safety and efficacy.

Formula: C₂₂H₃₂O₃

InChI: InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChI key: InChIKey=FRQMUZJSZHZSGN-HBNHAYAOSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Synonyms:

• (6Alpha)-17-Hydroxy-6-Methylpregn-4-Ene-3,20-Dione
• (6Alpha,8Xi,9Xi,14Xi)-6-Methyl-3,20-Dioxopregn-4-En-17-Yl Acetate
• (6α)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione
• 17-Alpha-Hydroxy-6-Alpha-Methylpregn-4-Ene-3,20-Dione
• 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione
• 17-Hydroxy-6α-methylpregn-4-ene-3,20dione
• 17-Hydroxy-6α-methylprogesterone
• 17α-Hydroxy-6α-methylprogesterone
• 6α-Methyl-17-hydroxyprogesterone
• 6α-Methyl-17R-hydroxyprogesterone
• 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione
• 6α-Methyl-4-pregnen-17-α-ol-3,20-dione
• 6α-Methyl-4-pregnen-17α-ol-3,20-dione
• Hydroxymethylprogesterone
• Medoxyprogesterone
• Medroxiprogesterona
• Medroxy progesterone Base
• Medroxyprogesteron
• Medroxyprogesterone
• Nsc 27408
• Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-
• Pregn-4-ene-3,20-dione, 17-hydroxy-6α-methyl-
• Progesterone, 17-hydroxy-6α-methyl-

Medroxyprogesterone Acetate Related Compound B (17-Hydroxy-6α-methylpregn-4-ene-3,20-dione)

CAS: 520-85-4

Estrogens and progestins

Formula: C₂₂H₃₂O₃

Color and Shape: White Powder

Molecular weight: 344.23514

Ref: 45-1378023

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone

Purity: ≥98%

Molecular weight: 344.49g/mol

Ref: 54-BUP14912

Medroxyprogesterone

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Molecular weight: 344.49

Ref: 7W-GP3864

Medroxyprogesterone Acetate EP Impurity B (Medroxyprogesterone Acetate USP Related Compound B, Medroxyprogesterone)

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 344.50

Ref: 4Z-M-455

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone

Purity: 98%

Molecular weight: 344.5g/mol

Ref: 54-OR1024407

4-Pregnen-6a-methyl-17-ol-3,20-dione-2,2,4,6ß,21,21,21-d7

CAS: 520-85-4

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 351.54

Ref: 3U-D7071

MEDROXYPROGESTERONE

CAS: 520-85-4

Purity: 98%

Molecular weight: 344.494995117188

Ref: 10-F799493

Medroxyprogesterone

Controlled Product

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Color and Shape: Neat

Molecular weight: 344.49

Ref: 86-MM0635.00

Medroxyprogesterone

Controlled Product

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Color and Shape: Neat

Molecular weight: 344.49

Ref: 04-C14852000

Medroxyprogesterone

CAS: 520-85-4

Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.

Formula: C₂₂H₃₂O₃

Purity: 99.18% - 99.51%

Color and Shape: Crystals From Chloroform Solid

Molecular weight: 344.49

Ref: TM-T5040

Medroxy Progesterone

Controlled Product

CAS: 520-85-4

Impurity Medroxyprogesterone Acetate USP Related Compound B
Applications An orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.SMedroxyprogesterone Acetate USP Related Compound B.
References Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007), Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007), Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008), Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008),

Formula: C₂₂H₃₂O₃

Color and Shape: Neat

Molecular weight: 344.49

Ref: TR-M203550

Medroxyprogesterone

Controlled Product

CAS: 520-85-4

Medroxyprogesterone is a progestin that has been used in the treatment of endometriosis, premenstrual syndrome, and other medical conditions. It is also used as a contraceptive or to treat abnormal uterine bleeding. Medroxyprogesterone acetate has been shown to inhibit nitrite ion formation in the rat bowel disease model and to have a direct effect on the ovaries. This drug has also been found to increase enzyme activities related to cellular transformation. Medroxyprogesterone acetate is available in combination with nomegestrol acetate (NOMAC) for use as an oral contraceptive medication. The oral bioavailability of medroxyprogesterone acetate is increased by NOMAC, which acts as an inhibitor of first-pass metabolism in the liver.

Formula: C₂₂H₃₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 344.49 g/mol

Ref: 3D-FM32162

Medroxyprogesterone

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 344.50

Ref: 3B-M3113

4-Pregnen-6α-methyl-17-ol-3,20-dione-2,2,4,6,21,21,21-d7

Controlled Product

CAS: 520-85-4

Formula: C₂₂D₇H₂₅O₃

Color and Shape: Neat

Molecular weight: 351.54

Ref: TR-M203553

Medroxyprogesterone

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Molecular weight: 344.49

Ref: ST-EA-CP-P133015

Medroxyprogesterone Acetate EP Impurity B

CAS: 520-85-4

Formula: C₂₂H₃₂O₃

Molecular weight: 344.49

Ref: ST-EA-CP-M96011