CAS 52029-86-4

7-Oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid

Description:

7-Oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid is a complex organic compound characterized by its fused ring structure, which includes a benzimidazole and isoquinoline moiety. This compound typically exhibits properties such as being a solid at room temperature, with potential applications in medicinal chemistry due to its unique structural features that may interact with biological targets. The presence of the carboxylic acid functional group suggests it can participate in acid-base reactions and may exhibit solubility in polar solvents. Its oxo group contributes to its reactivity and potential for forming hydrogen bonds, which can influence its biological activity and interactions. The compound's molecular structure may also allow for various substitution patterns, which can be explored for enhancing its pharmacological properties. Overall, 7-Oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid represents a class of compounds that are of interest in the development of new therapeutic agents.

Formula: C₂₁H₁₄N₂O₅

InChI: InChI=1/C19H10N2O3.C2H4O2/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18;1-2(3)4/h1-9H,(H,23,24);1H3,(H,3,4)

SMILES: c1ccc2c(c1)nc1c3ccc(c4cccc(c34)c(=O)n21)C(=O)O.CC(=O)O

Synonyms:

• Sto-609

STO-609, 98%

CAS: 52029-86-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₉H₁₀N₂O₃·C₂H₄O₂

Purity: 98%

Color and Shape: Yellow, Solid

Molecular weight: 374.35

Ref: 02-J67344

7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE

CAS: 52029-86-4

Formula: C₁₉H₁₀N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 314.2943

Ref: IN-DA00D9QU

STO-609

CAS: 52029-86-4

STO-609

Purity: ≥95%

Molecular weight: 314.29g/mol

Ref: 54-BUP11962

STO-609

CAS: 52029-86-4

STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.

Formula: C₁₉H₁₀N₂O₃

Purity: 97.14% - 98.8%

Color and Shape: Solid

Molecular weight: 314.29

Ref: TM-T3546

7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid

Controlled Product

CAS: 52029-86-4

Applications 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid is a calcium/calmodulin-dependent protein kinase inhibitor and was found to upregulate various AhR target genes in human macrophages.
References Monteiro, P., et al.: Drug. Meta. Dispos., 36, 2556 (2008); Tokumitsu, H., et al.: J. Biol. Chem., 278, 10908 (2003); Tokumitsu, H., et al.: J. Biol. Chem., 277, 15813 (2002);

Formula: C₁₉H₁₀N₂O₃

Color and Shape: Neat

Molecular weight: 374.346

Ref: TR-O847425