CAS 52050-17-6: Glucosylsphingosine
Description:Glucosylsphingosine, also known as glucosylceramide, is a glycosphingolipid characterized by the presence of a glucose molecule linked to a sphingosine backbone. It plays a crucial role in cellular processes, including cell signaling and membrane structure. This compound is particularly significant in the context of certain metabolic disorders, such as Gaucher's disease, where its accumulation can lead to various health issues. Glucosylsphingosine is typically found in the membranes of cells, especially in the nervous system and immune cells, contributing to the formation of lipid rafts that facilitate cellular communication. Its structure consists of a long-chain fatty acid attached to the sphingosine, which influences its physical properties and biological functions. The compound is soluble in organic solvents but has limited solubility in water, reflecting its amphipathic nature. Understanding glucosylsphingosine's characteristics is essential for exploring its role in health and disease, as well as its potential as a therapeutic target in sphingolipid metabolism disorders.
Formula:C24H47NO7
InChI:InChI=1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21+,22-,23+,24+/m0/s1
InChI key:InChIKey=HHJTWTPUPVQKNA-JIAPQYILSA-N
SMILES:OCC1OC(OCC(N)C(O)C=CCCCCCCCCCCCCC)C(O)C(O)C1O
- Synonyms:
- (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
- (3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl beta-D-mannopyranoside
- Glucosyl psychosine
- Glucosyl sphingosine
- Glucosyl-C<sub>18</sub>-sphingosine
- Glucosylsphingosine
- Sphingosyl beta-glucoside
- beta-D-Glucopyranoside, 2-amino-3-hydroxy-4-octadecenyl, (R-(R*,S*-(E)))-
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl
- See more synonyms
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, 2-amino-3-hydroxy-4-octadecenyl, [R-[R*,S*-(E)]]-
- Glucosyl-C18-sphingosine
- β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl
- Glucopsychosine
- β-D-Glucopyranoside, 2-amino-3-hydroxy-4-octadecenyl, [R-[R*,S*-(E)]]-
- Glcsph d18:1 (GlcbSphingolipids)
- β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl
- (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-D-glucopyranoside