CAS 521-78-8: Trimipramine maleate
Description:Trimipramine maleate is a pharmaceutical compound primarily used as an antidepressant, classified within the tricyclic antidepressant (TCA) category. It is known for its ability to influence neurotransmitter levels in the brain, particularly norepinephrine and serotonin, thereby alleviating symptoms of depression. The maleate salt form enhances its solubility and stability, making it suitable for formulation in various dosage forms. Trimipramine exhibits sedative properties, which can be beneficial for patients with insomnia associated with depression. Its chemical structure includes a dibenzocycloheptene core, contributing to its pharmacological effects. Common side effects may include dry mouth, drowsiness, and weight gain, typical of many TCAs. Due to its potential for interactions with other medications and the risk of overdose, careful monitoring is essential during treatment. As with all antidepressants, it is crucial for patients to consult healthcare professionals for personalized advice and management of their condition.
Formula:C20H26N2·C4H4O4
InChI:InChI=1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=YDGHCKHAXOUQOS-BTJKTKAUSA-N
SMILES:O=C(O)C=CC(=O)O.C=1C=CC2=C(C1)N(C=3C=CC=CC3CC2)CC(C)CN(C)C
- Synonyms:
- 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-aminium acid maleate
- 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine (2Z)-but-2-enedioate
- 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-, maleate (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,β-trimethyl-, (2Z)-2-butenedioate (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,β-trimethyl-, (Z)-2-butenedioate (1:1)
- Surmontil maleate
- Trimeprimine maleate
- Trimeprimine monomaleate
- Trimipramine Hydrogen Maleate
- Trimipramine acid maleate
- See more synonyms
