CAS 52123-49-6

Cefazaflur sodium

Description:

Cefazaflur sodium is a broad-spectrum cephalosporin antibiotic, primarily used for its antibacterial properties. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it valuable in treating various infections. The compound is characterized by its beta-lactam structure, which is essential for its mechanism of action, as it inhibits bacterial cell wall synthesis. Cefazaflur sodium is typically administered via injection and is known for its stability in the presence of certain beta-lactamases, enzymes produced by some bacteria that confer resistance to other antibiotics. The sodium salt form enhances its solubility in aqueous solutions, facilitating its use in clinical settings. As with many antibiotics, it is important to monitor for potential side effects, including allergic reactions and gastrointestinal disturbances. Cefazaflur sodium's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for determining its efficacy and safety profile in therapeutic applications.

Formula: C₁₃H₁₃F₃N₆O₄S₃·Na

InChI: InChI=1S/C13H13F3N6O4S3.Na/c1-21-12(18-19-20-21)28-3-5-2-27-10-7(9(24)22(10)8(5)11(25)26)17-6(23)4-29-13(14,15)16;/h7,10H,2-4H2,1H3,(H,17,23)(H,25,26);/t7-,10-;/m1./s1

InChI key: InChIKey=YOMRWLSPHUXYDH-YZUKSGEXSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(CSC(F)(F)F)=O)C2=O)(SCC1CSC=3N(C)N=NN3)[H].[Na]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-7-[[2-[(trifluoromethyl)thio]acetyl]amino]-, sodium salt (1:1), (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-7-[[[(trifluoromethyl)thio]acetyl]amino]-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-7-[[[(trifluoromethyl)thio]acetyl]amino]-, monosodium salt, (6R-trans)-
• 52123-49-6
• Cefazaflur sodium
• Skf 59962
• Sodium (6R,7R)-3-(((1-Methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-7-(2-((trifluoromethyl)thio)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefazaflur

CAS: 52123-49-6

Ref: 7W-GA1032