CAS 52146-35-7

1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine

Description:

1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine, with the CAS number 52146-35-7, is a chemical compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. This compound features a phenyl group substituted with three methoxy groups at the 3, 4, and 5 positions, enhancing its lipophilicity and potentially influencing its biological activity. The presence of the piperazine moiety suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, as piperazine derivatives are often associated with various therapeutic effects, including anxiolytic and antidepressant properties. The trimethoxyphenyl substituent may also contribute to the compound's interaction with biological targets, possibly affecting receptor binding or enzyme inhibition. Additionally, the compound's solubility, stability, and reactivity can be influenced by the methoxy groups, which can participate in hydrogen bonding and affect the overall polarity of the molecule. Overall, this compound's unique structure positions it as a candidate for further research in drug development and related fields.

Formula: C₁₄H₂₂N₂O₃

InChI: InChI=1S/C14H22N2O3/c1-17-12-8-11(9-13(18-2)14(12)19-3)10-16-6-4-15-5-7-16/h8-9,15H,4-7,10H2,1-3H3

InChI key: InChIKey=OVEVYSWOILUFMF-UHFFFAOYSA-N

SMILES: C(C1=CC(OC)=C(OC)C(OC)=C1)N2CCNCC2

Synonyms:

• 1-(3,4,5-Trimethoxybenzyl)Piperazine
• N-(3,4,5-Trimethoxybenzyl)piperazine
• Piperazine, 1-(3,4,5-trimethoxybenzyl)-
• Piperazine, 1-[(3,4,5-trimethoxyphenyl)methyl]-
• 1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine
• 1-((3,4,5-Trimethoxyphenyl)methyl)piperazine

Piperazine, 1-[(3,4,5-trimethoxyphenyl)methyl]-

CAS: 52146-35-7

Formula: C₁₄H₂₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.3361

Ref: IN-DA00I9BV

Trimetazidine EP Impurity A

CAS: 52146-35-7

Formula: C₁₄H₂₂N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 266.34

Ref: 4Z-T-353

Trimetazidine EP Impurity A

CAS: 52146-35-7

Formula: C₁₄H₂₂N₂O₃

Molecular weight: 266.34

Ref: ST-EA-CP-T12001

1-(3,4,5-Trimethoxybenzyl)piperazine

Controlled Product

CAS: 52146-35-7

Impurity Trimetazidine EP impurity A
Applications 1-(3,4,5-Trimethoxybenzyl)piperazine is an impurity of Trimetazidine (T795610). Trimetazidine impurity A.
References Ohtaka, H., et al.: Chem. Pharmaceut. Bull., 35, 2782 (1987),

Formula: C₁₄H₂₂N₂O₃

Color and Shape: White To Off-White

Molecular weight: 266.34

Ref: TR-T796025

1-(3,4,5-Trimethoxybenzyl)piperazine

Controlled Product

CAS: 52146-35-7

1-(3,4,5-Trimethoxybenzyl)piperazine is a pharmacological compound that inhibits the activity of multidrug resistance proteins. It modulates the activity of these proteins by binding to them and preventing efflux from cells. It also enhances the uptake of drugs into cells. This compound has been shown to be a potent inhibitor of P-glycoprotein in k562 cells and may be effective in treating multidrug resistant cancers.

Formula: C₁₄H₂₂N₂O₃

Purity: Min. 95%

Molecular weight: 266.34 g/mol

Ref: 3D-IT63856