CAS 52152-93-9

Cefsulodin sodium

Description:

Cefsulodin sodium is a semisynthetic antibiotic belonging to the class of cephalosporins, specifically designed to combat a range of bacterial infections. It is particularly effective against Pseudomonas aeruginosa and other Gram-negative bacteria. The compound is characterized by its broad-spectrum antibacterial activity, which is attributed to its ability to inhibit bacterial cell wall synthesis. Cefsulodin sodium is typically administered via injection and is often used in clinical settings for treating infections in immunocompromised patients or those with specific bacterial strains resistant to other antibiotics. The substance is soluble in water, which facilitates its use in intravenous formulations. Its chemical structure includes a beta-lactam ring, a hallmark of cephalosporins, contributing to its mechanism of action. As with many antibiotics, the use of cefsulodin sodium should be guided by susceptibility testing to minimize the risk of resistance development. Potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood cell counts, necessitating careful monitoring during treatment.

Formula: C₂₂H₁₉N₄O₈S₂·Na

InChI: InChI=1/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1

InChI key: InChIKey=GTZPOHRNWUTXNB-DWBVFMGKSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC([C@H](S(=O)(=O)O)C3=CC=CC=C3)=O)C2=O)(SCC1C[N+]=4C=CC(C(N)=O)=CC4)[H].[Na]

Synonyms:

• (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 7-(<span class="text-smallcaps">D</span>-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt
• <span class="text-smallcaps">D</span>-(-)-SCE-129
• Abbot 46811
• Cefomonil
• Cefsulodin
• Cefsulodin Sodium
• Cefsulodine sodium
• Cgp 7174E
• Monaspor
• Monosodium cefsulodin
• Pseudocef
• Pseudomonil
• Pyocefal
• Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, sodium salt (1:1)
• Pyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt
• Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, monosodium salt, [6R-[6α,7β(R*)]]-
• Pyridinium, 4-(aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt, [6R-[6α,7β(R*)]]-
• Sce 129
• Sodium (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[[(2R)-2-phenyl-2-sulfonatoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Sodium 3-[(4-Carbamoylpyridinium-1-Yl)Methyl]-8-Oxo-7-{[Phenyl(Sulfonato)Acetyl]Amino}-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
• Sodium cefsulodin
• Sulcephalosporin
• Takesulin
• Tilmapor
• Ulfar
• [6R-(6a,7b)]-4-(Aminocarbonyl)-1-[[2-carboxy-8-oxo-7-[(phenylsulfoacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium inner salt monosodium salt
• sodium (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[(2R)-2-phenyl-2-sulfonatoacetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium (6R,7R)-3-[(4-carbamoylpyridinium-1-yl)methyl]-8-oxo-7-{[phenyl(sulfonato)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 7-(D-α-Sulfophenylacetamido)ceph-3-em-3-(4′-carbamoylpyridinium)methyl-4-carboxylate sodium salt
• abbott-46811
• CEFSULODIN SODIUM SALT HYDRATE
• 4-(aminocarbonyl)-1-((2-carboxy-8-oxo-7-((phenylsulfoacetyl)amino)-pyridiniu
• pyridinium,4-(aminocarbonyl)-1-[[(6r,7r)-2-carboxy-8-oxo-7-[[(2r)-phenylsulfoa
• ulfaret
• 5-thio-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-,hydroxide,innersalt,monos
• cetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,innersalt,mono
• CEFSULONDIN SODIUM
• D-(-)-SCE-129
• cgp7174e
• (6r-(6-alpha,7-beta(r*)))-odiumsal
• 4-(AMinocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]aMino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM
• (6R,7R)-3-[(4-Carbamoylpyridinio)methyl]-8-oxo-7-[(R)-2-phenyl-2-sulfoacetylamino]-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• Cefsulodin SodiuM Hydrate
• (6R,7R)-3-[(4-Carbamoylpyridinio)methyl]-8-oxo-7-[(R)-2-phenyl-2-(sodiosulfo)acetylamino]-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• hydrogen [6R-[6alpha,7beta(R*)]]-4-carbamoyl-1-[[2-carboxylato-8-oxo-7-(phenylsulphonatoacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium, monosodium salt
• Cefsulodin hydrate sodium salt
• sce129
• CEFSULODIN SODIUM SALT

CEFSULODIN SODIUM SALT, HYDRATE

CAS: 52152-93-9

Formula: C₂₂H₁₉N₄NaO₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 554.5280

Ref: IN-DA003OQF

Cefsulodin sodium salt hydrate

CAS: 52152-93-9

Formula: C₂₂H₁₉N₄NaO₈S₂·xH₂O

Purity: ≥ 86.0%

Color and Shape: White to light yellow powder

Molecular weight: 554.53 (anhydrous)

Ref: 7W-GA1461

Cefsulodin sodium salt

CAS: 52152-93-9

Cefsulodin sodium salt

Formula: C₂₂H₂₀N₄O₈S₂·Na

Purity: By hplc: 96.5% by area (Typical Value in Batch COA)

Color and Shape: off white to faint yellow powder

Molecular weight: 555.54g/mol

Ref: 54-BIC0112

Cefsulodin sodium

CAS: 52152-93-9

Cefsulodin sodium

Purity: ≥98%

Molecular weight: 554.52g/mol

Ref: 54-BUP15106

Cefsulodin sodium

CAS: 52152-93-9

Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.

Formula: C₂₂H₁₉N₄NaO₈S₂

Purity: 98.48% - 99.3%

Color and Shape: White To Pale Yellow Crystalline Powder

Molecular weight: 554.52

Ref: TM-T0827

Cefsulodin Sodium Salt

Controlled Product

CAS: 52152-93-9

Applications Cefsulodin is a third generation cephalosporin (C258750) antibiotic designed specifically for Pseudomonas Aeruginosa.
References Newall, C.E., et al.: Comprehen. Med. Chem., 2, 609 (1990); Zhao, W.H., et al.: J. Med. MIcrobiol., 57, 974 (2008); Goto, H., et al.: Jap. J. Antibio., 61, 209 (2008);

Formula: C₂₂H₁₉N₄O₈S₂·Na

Color and Shape: Off White

Molecular weight: 554.53

Ref: TR-C248090

Cefsulodin sodium salt (SCE-129), Antibiotic for Culture Media Use Only

CAS: 52152-93-9

Cefsulodin sodium salt is a beta lactam antibiotic in the third-generation cephalosporin family that inhibits penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis.

Formula: C₂₂H₁₉N₄NaO₈S₂

Purity: Min. 97.0 Area-%

Molecular weight: 554.53 g/mol

Ref: 3D-C-2490

Cefsulodin Sodium Salt Hydrate

CAS: 1426397-23-0, 52152-93-9, 62587-73-9

Formula: C₂₂H₁₉N₄NaO₈S₂·xH₂O

Purity: >95.0%(HPLC)(N)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 554.52 (as Anhydrous)

Ref: 3B-C2598

Cefsulodin Sodium Salt (CFS) extrapure, 97%

CAS: 52152-93-9

Formula: C₂₂H₁₉N₄NaO₈S₂

Purity: min. 97%

Color and Shape: Off-white to pale yellow, Crystalline powder

Molecular weight: 554.53 (anhy)

Ref: SR-80223

Cefsulodin sodium salt (SCE-129), Antibiotic for Culture Media Use Only

CAS: 52152-93-9

Cefsulodin sodium salt is a beta lactam antibiotic in the third-generation cephalosporin family that inhibits penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis.

Formula: C₂₂H₁₉N₄NaO₈S₂

Purity: Min. 97.0 Area-%

Molecular weight: 554.53 g/mol

Ref: 3D-C-2492