CAS 52157-91-2

Galosemide

Description:

Galosemide, identified by its CAS number 52157-91-2, is a chemical compound that belongs to the class of sulfonamides. It is characterized by its structural features, which include a sulfonamide group that contributes to its biological activity. Galosemide is primarily recognized for its potential use in pharmacological applications, particularly in the context of diuretic and antihypertensive effects. The compound exhibits properties that may influence electrolyte balance and fluid regulation in biological systems. Its mechanism of action typically involves inhibition of specific transporters or enzymes, leading to increased excretion of sodium and water. Additionally, galosemide may have implications in research related to cardiovascular health and fluid management. As with many sulfonamides, it is essential to consider its solubility, stability, and interaction with other compounds when evaluating its practical applications. Safety and toxicity profiles are also critical for understanding its suitability for therapeutic use. Overall, galosemide represents a compound of interest in medicinal chemistry and pharmacology.

Formula: C₁₅H₁₄F₃N₃O₃S

InChI: InChI=1/C15H14F3N3O3S/c1-2-14(22)21-25(23,24)13-9-19-7-6-12(13)20-11-5-3-4-10(8-11)15(16,17)18/h3-9H,2H2,1H3,(H,19,20)(H,21,22)

SMILES: CCC(=NS(=O)(=O)c1c[nH]ccc1=Nc1cccc(c1)C(F)(F)F)O

Synonyms:

• Galosemide [INN]
• Gallosemide
• Brn 0501125
• C 2124
• Galosemida
• Galosemida [INN-Spanish]
• Galosemidum
• Galosemidum [INN-Latin]
• N-((4-((3-(Trifluoromethyl)phenyl)amino)-3-pyridinyl)sulfonyl)propanamide
• N-((4-(alpha,alpha,alpha-Trifluoro-3-toluidino)-3-pyridyl)sulfonyl)propionamid
• N-((4-(alpha,alpha,alpha-Trifluoro-m-toluidino)-3-pyridyl)sulfonyl)propionamide
• Unii-J8Qb2W9908
• Propanamide, N-((4-((3-(trifluoromethyl)phenyl)amino)-3-pyridinyl)sulfonyl)-
• N-[(4-{[3-(trifluoromethyl)phenyl]amino}pyridin-3-yl)sulfonyl]propanamide
• 5-22-14-00461 (Beilstein Handbook Reference)
• Galosemide
• N-[4-[3-(trifluoromethyl)anilino]pyridin-3-yl]sulfonylpropanamide
• N-[4-[[3-(trifluoromethyl)phenyl]amino]pyridin-3-yl]sulfonylpropanamide

Galosemide

Controlled Product

CAS: 52157-91-2

Applications Galosemide is a compound with diuretic activity.
References Delarge, J., Ghys, A.: Ann Pharm Fr, 39, 59 (1981);

Formula: C₁₅H₁₄F₃N₃O₃S

Color and Shape: Neat

Molecular weight: 373.35

Ref: TR-G596625

Galosemide

CAS: 52157-91-2

Galosemide is a drug that belongs to the class of organic acids. It is used in the treatment of congestive heart failure and hypertension. This drug binds to specific target proteins, which are present in the heart muscle cells, to lower blood pressure by preventing arrhythmia. The trifluoromethyl group on galosemide allows it to bind with high affinity and specificity to these target proteins. Galosemide also has been shown to affect cardiac metabolism by lowering levels of lipids (dyslipidemia) and reducing ventricular dysfunction due to its ability to decrease cardiac energy consumption. Galosemide may be administered orally or intravenously as a reconstituted solution. It can be diluted with water for injection or mixed with other diluents such as glucose, mannitol, dextrose, or sodium chloride for oral use.

Formula: C₁₅H₁₄F₃N₃O₃S

Purity: Min. 95%

Molecular weight: 373.4 g/mol

Ref: 3D-CCA15791