CAS 52169-36-5

Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, potassium salt (1:1)

Description:

Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, potassium salt (1:1) is a complex organic compound characterized by its structural components, which include a benzamide moiety, a chloro substituent, and a sulfonamide group. The presence of the cyclohexylamino group suggests potential biological activity, possibly as a pharmaceutical agent. This compound is typically a white to off-white solid and is soluble in polar solvents due to its ionic nature as a potassium salt. Its molecular structure indicates potential interactions with biological targets, making it of interest in medicinal chemistry. The compound may exhibit properties such as moderate to high melting points and stability under standard laboratory conditions. Additionally, its synthesis involves multiple steps, including the formation of amide and sulfonamide linkages, which are common in drug development. As with many organic compounds, safety data should be consulted for handling and usage, particularly regarding its potential toxicity and environmental impact.

Formula: C₂₃H₂₇ClKN₃O₅S

InChI: InChI=1S/C23H28ClN3O5S.K/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18;/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29);

InChI key: InChIKey=WUVNANLGKVVVAV-UHFFFAOYSA-N

SMILES: C(NCCC1=CC=C(S(NC(NC2CCCCC2)=O)(=O)=O)C=C1)(=O)C3=C(OC)C=CC(Cl)=C3.[K]

Synonyms:

• Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, potassium salt (1:1)
• Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, monopotassium salt
• Potassium glibenclamide
• KAJMFLAYIQKSQT-UHFFFAOYSA-N
• Glyburide Potassium
• Glyburide (potassium salt)

Glibenclamide potassium

CAS: 52169-36-5

Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.

Formula: C₂₃H₂₇ClKN₃O₅S

Color and Shape: Solid

Molecular weight: 532.09

Ref: TM-T72272

Glyburide potassium

CAS: 52169-36-5

Glyburide potassium is a drug that belongs to the class of sulfonylureas and is used as an oral hypoglycemic agent. It acts by stimulating pancreatic beta cells to release insulin. Glyburide potassium has been shown to increase intracellular Ca2+ levels, inhibit ATP-sensitive K+ channels, and stimulate enzyme activities in human erythrocytes. The drug also inhibits sodium carbonate-induced ionotropic gelation in aqueous solutions. Glyburide potassium has been shown to be a potent inhibitor of high-sensitivity C-reactive protein (hsCRP) activity in vitro. It also inhibits neuronal function in vitro through its effects on monoclonal antibodies.

Formula: C₂₃H₂₈ClKN₃O₅S

Purity: Min. 95%

Molecular weight: 533.1 g/mol

Ref: 3D-CCA16936

Glyburide Potassium Salt

CAS: 52169-36-5

Formula: C₂₃H₂₈ClN₃O₅SK

Molecular weight: 493.00 : 39.10

Ref: ST-EA-CP-G8009