CAS: 521984-48-5 - 6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-enoyl]-1,2,3,4-tetrahydroisoquinoline hydrochloride

Formula: C₂₈H₂₈ClN₃O₃

InChI: InChI=1/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,18H2,1-3H3;1H/b12-11+;

SIS3 hydrochloride

CAS: 521984-48-5

• Formula: C₂₈H₂₈ClN₃O₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 489.9932

SIS3

CAS: 521984-48-5

• Formula: C₂₈H₂₇N₃O₃·HCl
• Molecular weight: 489.99

SIS 3 Hydrochloride

CAS: 521984-48-5

• Formula: C₂₈H₂₇N₃O₃·HCl
• Purity: >98.0%(HPLC)
• Color and Shape: Light yellow to Brown powder to crystal
• Molecular weight: 490.00

(E)-SIS3

CAS: 521984-48-5

(E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding

• Formula: C₂₈H₂₇N₃O₃·HCl
• Purity: 95.64% - 98.83%
• Color and Shape: Solid
• Molecular weight: 489.99

1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline Monohydrochloride

CAS: 521984-48-5

Applications 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline Monohydrochloride is a potent and selective Smad3 inhibitor that attenuates transforming growth factor …

• Formula: C₂₈H₂₇N₃O₃·HCl
• Color and Shape: Neat
• Molecular weight: 489.993

SIS3

CAS: 521984-48-5

SIS3 is a small molecule that inhibits the TGF-β signaling pathway. It has minimal toxicity …

• Formula: C₂₈H₂₇N₃O₃·HCl
• Purity: Min. 95%
• Molecular weight: 489.99 g/mol