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CAS 522-48-5

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Tetrahydrozoline hydrochloride

Description:
Tetrahydrozoline hydrochloride is a sympathomimetic agent primarily used as a topical vasoconstrictor in ophthalmic solutions to relieve redness in the eyes. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range typically between 4.5 and 6.5 when dissolved. The compound acts by stimulating alpha-adrenergic receptors, leading to the constriction of blood vessels in the conjunctiva, thereby reducing redness. Tetrahydrozoline hydrochloride is often found in over-the-counter eye drops and nasal decongestants. Its chemical formula is C13H18N2·HCl, and it has a molecular weight that reflects its structure, which includes a phenolic ring and an imidazoline moiety. While generally safe for short-term use, prolonged exposure or excessive dosage can lead to side effects such as rebound congestion or ocular irritation. As with any medication, it is important to follow dosing guidelines and consult healthcare professionals for appropriate use.
Formula:C13H16N2·ClH
InChI:InChI=1S/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13;/h1-2,4,6,12H,3,5,7-9H2,(H,14,15);1H
InChI key:InChIKey=BJORNXNYWNIWEY-UHFFFAOYSA-N
SMILES:C1(C=2C(CCC1)=CC=CC2)C=3NCCN3.Cl
Synonyms:
  • 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1)
  • 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, monohydrochloride
  • 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline hydrochloride
  • 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride
  • 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride (1:1)
  • 2-Imidazoline, 2-(1,2,3,4-tetrahydro-1-naphthyl)-, monohydrochloride
  • 2-Tetralin-1-Yl-4,5-Dihydro-1H-Imidazole Hydrochloride
  • Murine Plus
  • Soothe
  • Tetrahydrozoline Hcl
  • See more synonyms
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