CAS 522-51-0

Dequalinium chloride

Description:

Dequalinium chloride is a quaternary ammonium compound characterized by its broad-spectrum antimicrobial properties. It appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various applications, particularly in pharmaceuticals and personal care products. The compound is known for its effectiveness against a range of bacteria and fungi, which makes it valuable in antiseptic formulations and as a preservative. Dequalinium chloride functions by disrupting microbial cell membranes, leading to cell death. It is often used in throat lozenges, mouthwashes, and topical antiseptics. Additionally, it has been investigated for its potential use in treating infections and as a disinfectant. While generally considered safe when used as directed, it can cause irritation in some individuals, particularly in sensitive areas. As with any chemical substance, proper handling and adherence to safety guidelines are essential to minimize risks associated with exposure.

Formula: C₃₀H₄₀N₄·2Cl

InChI: InChI=1S/C30H38N4.2ClH/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34;;/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3;2*1H

InChI key: InChIKey=LTNZEXKYNRNOGT-UHFFFAOYSA-N

SMILES: C(CCCCCCCCC[N+]=1C2=C(C(N)=CC1C)C=CC=C2)[N+]=3C4=C(C(N)=CC3C)C=CC=C4.[Cl-]

Synonyms:

• 1,1'-Decane-1,10-Diylbis(4-Amino-2-Methylquinolinium) Dichloride
• 1,1′-Decamethylenebis[4-aminoquinaldinium chloride]
• Badq 10
• Baqd 10
• Decamethylenebis[4-aminoquinaldinium chloride]
• Decamine
• Decamine (pharmaceutical)
• Decatylen
• Dekadin
• Dekamiln
• Dekamin
• Dequacets
• Dequadin
• Dequadin chloride
• Dequafungen
• Dequalinum Chloride
• Dequavagyn
• Dequavet
• Efisol
• Eriosept
• Evazol
• Fluomizin
• Fluomycin N
• Grocreme
• Ivazil
• Labosept
• Ldn 0096422
• NSC 166454
• Optipect
• Oralgol
• Phylletten
• Polycidine
• Quinaldinium, 1,1′-decamethylenebis[4-amino-, dichloride
• Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2)
• Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride
• Rumilet
• Sanoral
• Sentril

DEQUALINIUM CHLORIDE FOR ID CRS

CAS: 522-51-0

DEQUALINIUM CHLORIDE FOR ID CRS

Ref: 41-Y0002332

DEQUALINIUM FOR SYSTEM SUITABILITY CRS

CAS: 522-51-0

DEQUALINIUM FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002333

Dequalinium Chloride

CAS: 522-51-0

Formula: C₃₀H₄₀Cl₂N₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 527.5714

Ref: IN-DA019FVH

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.

Formula: C₃₀H₄₀Cl₂N₄

Purity: 99.79% - 99.9%

Color and Shape: Solid

Molecular weight: 527.59

Ref: TM-T0979

1,1'-(Decane-1,10-Diyl)Bis(4-Amino-2-Methylquinolin-1-Ium) Chloride

CAS: 522-51-0

1,1'-(Decane-1,10-Diyl)Bis(4-Amino-2-Methylquinolin-1-Ium) Chloride

Purity: 98%

Molecular weight: 527.57g/mol

Ref: 54-OR1026217

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride

Purity: ≥98%

Molecular weight: 527.59g/mol

Ref: 54-BUP14027

Dequalinium Dichloride

CAS: 522-51-0

Formula: C₃₀H₄₀N₄·2Cl

Color and Shape: Off-White Solid

Molecular weight: 456.68 2*35.45

Ref: 4Z-D-084004

Dequalinium Chloride

CAS: 522-51-0

Formula: C₃₀H₄₀N₄Cl

Color and Shape: Neat

Molecular weight: 527.57

Ref: 86-MM1705.00

Dequalinium chloride

CAS: 522-51-0

Formula: C₃₀H₄₀Cl₂N₄·xH₂O

Purity: 95.0 - 101.0 % (dried basis)

Color and Shape: White, off-white or light yellow powder

Molecular weight: 527.57 (anhydrous)

Ref: 7W-GE7850

Dequalinium-d8 DiChloride

CAS: 522-51-0

Formula: C₃₀H₃₂D₈N₄·2Cl

Molecular weight: 464.73 2*35.45

Ref: 4Z-D-084010

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride is a quaternary ammonium compound that has been discovered to be an inhibitor of the cytopathic effects of some syndrome viruses. It is able to inhibit the replication of the virus in various clinical isolates and in cell culture models. Dequalinium chloride also inhibits acetylcholine receptor-mediated endocytosis, which is one of the mechanisms by which cells resist infection. The mechanism by which dequalinium chloride inhibits acetylcholine receptor-mediated endocytosis is not yet known, but it has been suggested that it might be due to its inhibitory activity on mitochondrial uncoupler proteins. This property may make dequalinium chloride an effective treatment against bacterial infections and respiratory diseases such as cystic fibrosis and asthma.

Formula: C₃₀H₄₀Cl₂N₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 527.57 g/mol

Ref: 3D-FD40542

Dequalinium chloride

CAS: 522-51-0

Purity: 99%

Molecular weight: 526.263

Ref: 10-F797293

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride is a novel, broad spectrum antimicrobial agent with a mechanism of action that inhibits the mitochondria-dependent respiratory chain. Studies have shown that it inhibits the growth of resistant microorganisms in cell-based experiments and in bacterial infections. Dequalinium chloride also has cytopathic effects on thp-1 cells, which are specific for Mycobacterium tuberculosis. In addition to inhibiting mitochondria-dependent respiration, this compound also increases acetylcholine receptor sensitivity in A549 lung cancer cells. Dequalinium chloride is a quaternary ammonium cation and has been shown to be effective against clinical isolates and inhibitory concentrations of a variety of virus species, including human rhinovirus (HRV) and Coxsackie virus type B4 (CoxB4).

Formula: C₃₀H₄₀Cl₂N₄

Purity: Min. 95.0 Area-%

Molecular weight: 527.57 g/mol

Ref: 3D-W-105841

Dequalinium Chloride

CAS: 522-51-0

Color and Shape: Neat

Ref: 61-FOR1705.00