CAS 522-57-6

Papaveraldine

Description:

Papaveraldine, with the CAS number 522-57-6, is an alkaloid derived from the opium poppy, Papaver somniferum. It is structurally related to other opiate compounds and exhibits a complex molecular framework. Papaveraldine is characterized by its unique bicyclic structure, which contributes to its pharmacological properties. The substance is known for its potential analgesic effects, although it is less commonly studied compared to more prominent opiates. In terms of solubility, papaveraldine is typically soluble in organic solvents, which is a common trait among many alkaloids. Its biological activity may involve interactions with opioid receptors, although specific mechanisms and effects can vary. As with many alkaloids, safety and toxicity profiles are important considerations, and its use is subject to regulatory scrutiny due to its association with narcotic substances. Overall, papaveraldine represents a fascinating area of study within the field of medicinal chemistry, particularly in the context of pain management and the development of new therapeutic agents.

Formula: C₂₀H₁₉NO₅

InChI: InChI=1S/C20H19NO5/c1-23-15-6-5-13(10-16(15)24-2)20(22)19-14-11-18(26-4)17(25-3)9-12(14)7-8-21-19/h5-11H,1-4H3

InChI key: InChIKey=QJTBIAMBPGGIGI-UHFFFAOYSA-N

SMILES: C(=O)(C=1C2=C(C=C(OC)C(OC)=C2)C=CN1)C3=CC(OC)=C(OC)C=C3

Synonyms:

• (6,7-Dimethoxy-1-isoquinolinyl)(3,4-dimethoxyphenyl)methanone
• (6,7-Dimethoxyisoquinolin-1-Yl)(3,4-Dimethoxyphenyl)Methanone
• 6,7-Dimethoxy-1-veratroylisoquinoline
• Ketone, 6,7-dimethoxy-1-isoquinolyl 3,4-dimethoxyphenyl
• Ketone, 6,7-dimethoxy-1-isoquinolyl 3,4-dimethoxyphenyl (8CI)
• Methanone, (6,7-dimethoxy-1-isoquinolinyl)(3,4-dimethoxyphenyl)-
• Methanone, (6,7-dimethoxy-1-isoquinolinyl)(3,4-dimethoxyphenyl)- (9CI)
• Nsc 94266
• Papaveraldin
• Papaveraldine
• Xanthaline

Papaverine EP Impurity D (Papaveraldine)

CAS: 522-57-6

Formula: C₂₀H₁₉NO₅

Color and Shape: Pale Yellow Solid

Molecular weight: 353.37

Ref: 4Z-P-484

Papaveraldine

Controlled Product

CAS: 522-57-6

Applications Papaveraldine is an impurity of Papaverine (P190500), a smooth muscle relaxant found in opium. Vasodilator (cerebral).
References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988)

Formula: C₂₀H₁₉NO₅

Color and Shape: Neat

Molecular weight: 353.30

Ref: TR-P190400

Papaveraldine

CAS: 522-57-6

Papaveraldine is a benzylisoquinoline alkaloid that papaverine degradation product.

Formula: C₂₀H₁₉NO₅

Color and Shape: Solid

Molecular weight: 353.37

Ref: TM-T33879

Papaveraldine

CAS: 522-57-6

Papaverine is a plant alkaloid that has been shown to be effective as an analgesic and anti-inflammatory agent. It is used in the treatment of chronic pain and inflammation, but its mechanism of action is not well understood. Papaverine has been shown to inhibit the production of growth factors, such as platelet-derived growth factor (PDGF), by cells. Papaverine also has effects on the immune system and may act through toll-like receptor 4 (TLR4) to inhibit tumor cell proliferation. The effective dose for papaverine ranges from 1 mg to 10 mg per day, depending on the condition being treated. This drug can be administered orally or intravenously as a pharmaceutical preparation.

Formula: C₂₀H₁₉NO₅

Purity: Min. 95%

Molecular weight: 353.4 g/mol

Ref: 3D-AAA52257

Papaverine EP Impurity D

CAS: 522-57-6

Formula: C₂₀H₁₉NO₅

Molecular weight: 353.37

Ref: ST-EA-CP-P47009