CAS 522-66-7

(-)-Dihydroquinine

Description:

(-)-Dihydroquinine is a naturally occurring alkaloid derived from the bark of the cinchona tree, known for its use as an antimalarial agent and as a bittering agent in tonic water. It is a stereoisomer of dihydroquinine, characterized by its specific three-dimensional arrangement of atoms, which contributes to its biological activity. The compound has a molecular formula that includes carbon, hydrogen, and nitrogen, reflecting its organic nature. (-)-Dihydroquinine exhibits a chiral center, leading to its optical activity, and it typically appears as a white to off-white crystalline solid. Its solubility varies in different solvents, being more soluble in polar solvents like water and ethanol. The compound has a relatively low toxicity profile, making it suitable for use in food and pharmaceutical applications. Additionally, it has been studied for its potential effects on various biological systems, including its role in modulating ion channels and its use in the synthesis of other chemical compounds. Overall, (-)-Dihydroquinine is significant in both medicinal chemistry and natural product research.

Formula: C₂₀H₂₆N₂O₂

InChI: InChI=1S/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m0/s1

InChI key: InChIKey=LJOQGZACKSYWCH-WZBLMQSHSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](CC)[C@](C3)(CC4)[H])[H]

Synonyms:

• 10,11-Dihydroquinine
• Hydroquinine
• Dihydroquinine
• Cinchonan-9-ol, 10,11-dihydro-6′-methoxy-, (8α,9R)-
• (8α,9R)-10,11-Dihydro-6′-methoxycinchonan-9-ol

(-)-Dihydroquinine

CAS: 522-66-7

Formula: C₂₀H₂₆N₂O₂

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 326.44

Ref: 3B-D6112

Dihydroquinine (R-[(2S,4S,5R)-5-Ethylquinuclidin-2-yl](6-methoxyquinolin-4-yl)methanol)

CAS: 522-66-7

Alkaloids of cinchona (excluding quinine and its salts) and their derivatives; salts thereof

Formula: C₂₀H₂₆N₂O₂

Color and Shape: Off-White Solid

Molecular weight: 326.19943

Ref: 45-1A08680

(1R)-((2S,4S,5R)-5-Ethyl-quinuclidine-2-yl)(6-methoxy-quinolin-4-yl)methanol

CAS: 522-66-7

Formula: C₂₀H₂₆N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 326.4326

Ref: IN-DA0037RI

Hydroquinine

CAS: 522-66-7

Hydroquinine

Purity: ≥98%

Molecular weight: 326.43g/mol

Ref: 54-BUP18119

(-)-Dihydroquinine

CAS: 522-66-7

(-)-Dihydroquinine

Formula: C₂₀H₂₆N₂O₂

Purity: 98%

Color and Shape: white to gray solid

Molecular weight: 326.43g/mol

Ref: 54-OR1007777

Dihydro-Quinine

CAS: 522-66-7

Formula: C₂₀H₂₆N₂O₂

Molecular weight: 326.44

Ref: 4Z-Q-0410

Hydroquinine

CAS: 522-66-7

Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.

Formula: C₂₀H₂₆N₂O₂

Purity: 99.42%

Color and Shape: Solid

Molecular weight: 326.43

Ref: TM-T7126

(-)-dihydroquinine

CAS: 522-66-7

Cinchona alkaloid

Formula: C₂₀H₂₆N₂O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 326.44

Ref: 5G-80965

(-)-Dihydroquinine

Controlled Product

CAS: 522-66-7

Applications (-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.
References Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 12, 547 (1983); Kremsner, P.G., et al.: J. Infect. Dis., 169, 467 (1994);

Formula: C₂₀H₂₆N₂O₂

Color and Shape: Neat

Molecular weight: 326.43

Ref: TR-D449915

Quinine EP Impurity C

CAS: 522-66-7

Formula: C₂₀H₂₆N₂O₂

Molecular weight: 326.43

Ref: ST-EA-CP-Q3003

Hydroquinine

CAS: 522-66-7

Hydroquinine is a quinidine derivative that is used in the treatment of malaria, as well as cardiac and infectious diseases. It is also used to measure the concentration of hydroquinine in urine. Hydroquinine inhibits the production of dopamine, which is necessary for the transmission of impulses in the central nervous system. This drug has been shown to have both atrial and ventricular effects, with an increased risk of cardiac arrhythmias. Hydroquinine can be used in chemical inhibition studies because it can bind to a variety of ligands, such as dihydroquinidine and papillary muscle.

Formula: C₂₀H₂₆N₂O₂

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 326.43 g/mol

Ref: 3D-FH30590

(1R)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

CAS: 522-66-7

Formula: C₂₀H₂₆N₂O₂

Purity: 95%

Color and Shape: Beige powder

Molecular weight: 326.44

Ref: 10-F093441