CAS 52222-73-8

1H-Pyrazole, 4-(trifluoromethyl)-

Description:

1H-Pyrazole, 4-(trifluoromethyl)-, with the CAS number 52222-73-8, is an organic compound characterized by its pyrazole ring structure, which is a five-membered ring containing two nitrogen atoms. The presence of a trifluoromethyl group (-CF3) at the 4-position significantly influences its chemical properties, enhancing its lipophilicity and potentially its reactivity. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It is known for its applications in pharmaceuticals and agrochemicals, often serving as an intermediate in the synthesis of various biologically active compounds. The trifluoromethyl group imparts unique electronic properties, making it a valuable moiety in medicinal chemistry. Additionally, 1H-Pyrazole derivatives are often studied for their potential anti-inflammatory, analgesic, and antimicrobial activities. Handling this compound requires standard safety precautions, as with many fluorinated compounds, due to potential toxicity and environmental concerns.

Formula: C₄H₃F₃N₂

InChI: InChI=1S/C4H3F3N2/c5-4(6,7)3-1-8-9-2-3/h1-2H,(H,8,9)

InChI key: KDEJQUNODYXYBJ-UHFFFAOYSA-N

SMILES: C1=C(C=NN1)C(F)(F)F

4-(Trifluoromethyl)pyrazole

CAS: 52222-73-8

Formula: C₄H₃F₃N₂

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 136.08

Ref: 3B-T3076

4-Trifluoromethyl-1H-pyrazole, 97%

CAS: 52222-73-8

It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles. This Thermo Scientific Chemicals brand product was originally part of the A

Formula: C₄H₃F₃N₂

Purity: 97%

Color and Shape: White to yellow to orange, Crystals or powder or crystalline powder

Molecular weight: 136.08

Ref: 02-H34396

4-(Trifluoromethyl)-1H-pyrazole

CAS: 52222-73-8

4-(Trifluoromethyl)-1H-pyrazole

Formula: C₄H₃F₃N₂

Purity: 99%

Color and Shape: Solid-Powder

Molecular weight: 136.07522

Ref: 54-PC49544

4-(Trifluoromethyl)-1H-pyrazole

CAS: 52222-73-8

Formula: C₄H₃F₃N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 136.0752

Ref: IN-DA0038OT

4-(Trifluoromethyl)-1H-pyrazole

CAS: 52222-73-8

4-(Trifluoromethyl)-1H-pyrazole

Formula: C₄H₃F₃N₂

Purity: 97%

Molecular weight: 136.08

Ref: IN-DG201028

4-(Trifluoromethyl)-1H-pyrazole

CAS: 52222-73-8

Formula: C₄H₃F₃N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 136.077

Ref: 10-F218047

4-Trifluoromethylpyrazole

Controlled Product

CAS: 52222-73-8

Formula: C₄H₃F₃N₂

Color and Shape: Neat

Molecular weight: 136.075

Ref: TR-T792080