CAS 52239-63-1

Butanedioic acid, 2-hydroxy-, compd. with 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2:1)

Description:

Butanedioic acid, 2-hydroxy-, compd. with 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2:1), identified by CAS number 52239-63-1, is a complex organic compound that features both a dicarboxylic acid and a phenothiazine derivative. The butanedioic acid component contributes to its acidic properties, while the hydroxy group enhances its solubility and reactivity. The phenothiazine moiety is known for its pharmacological properties, often associated with antipsychotic activity. The presence of the ethylthio group and the piperazine ring suggests potential interactions with biological systems, possibly influencing its pharmacokinetics and pharmacodynamics. This compound may exhibit characteristics such as moderate to high solubility in polar solvents, and its structure indicates potential for hydrogen bonding and other intermolecular interactions. Overall, this compound's unique combination of functional groups suggests it may have applications in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological activity and safety profiles would require further investigation through empirical studies.

Formula: C₂₂H₂₉N₃S₂·2C₄H₆O₅

InChI: InChI=1S/C22H29N3S2.C4H6O5/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24;5-2(4(8)9)1-3(6)7/h4-5,7-10,17H,3,6,11-16H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)

InChI key: InChIKey=TZWRZMNGFHAGHZ-UHFFFAOYSA-N

SMILES: C(CC(O)=O)(C(O)=O)O.C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SCC)C3

Synonyms:

• 10H-Phenothiazine, 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-, hydroxybutanedioate (1:2)
• 2-hydroxybutanedioic acid - 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (2:1)
• Butanedioic acid, 2-hydroxy-, compd. with 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2:1)
• Butanedioic acid, hydroxy-, compd. with 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2:1)
• Norzine
• Thiethylperazine Malate
• Thiethylperazine dimalate

Thiethylperazine Dimalate

CAS: 52239-63-1

Formula: C₂₂H₂₉N₃S₂·2C₄H₆O₅

Ref: TR-TRC-T344495

Thiethylperazine Dimalate

Controlled Product

CAS: 52239-63-1

Applications Thiethylperazine Dimalate is used as an anti-emetic drug specifically during pregnancy. Also a potent inhibitory agent against Enterococcus faecalis, a streptococcus Group D compound. Antibacterial.
References Czeizel, A. et al.: Int. J. Obst. Gynaecol., 110, 497 (2003); Rahbar, M. et al.: Bas. Clin. Pharmacol. Toxicol., 107, 676 (2010);

Formula: C₂₂H₂₉N₃S₂·2C₄H₆O₅

Color and Shape: Neat

Molecular weight: 667.79

Ref: TR-T344495

Thiethylperazine malate

CAS: 52239-63-1

Thiethylperazine malate is a drug with anti-inflammatory and anticonvulsant properties. It is used in the treatment of various symptoms such as pain, inflammation, and anxiety. Thiethylperazine malate has been studied for its clinical value in treating depression and anxiety disorders. The efficacy of this drug is thought to be due to its ability to block dopamine receptors in the brain, which prevents the release of excess dopamine in the central nervous system. This drug also binds to cannabinoid type 2 (CB2) receptors, which are found on immune cells. Studies show that thiethylperazine malate can inhibit the proliferation of cancer cells and radiation induced injury by inhibiting energy metabolism in cancer cells. This drug also increases urine output when given at a dose of 20mg/kg body weight (bw). Thiethylperazine malate is administered as a single dose intravenously or orally with pentobarbital sodium as an adjuvant.

Formula: C₂₂H₂₉N₃S₂·2C₄H₆O₅

Purity: Min. 95%

Molecular weight: 667.79 g/mol

Ref: 3D-FT43271