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CAS 5227-68-9

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guanine 7-oxide

Description:
Guanine 7-oxide, with the CAS number 5227-68-9, is a derivative of the nucleobase guanine, which is one of the building blocks of nucleic acids like DNA and RNA. This compound features an oxidation at the 7-position of the guanine structure, which can influence its biological activity and stability. Guanine 7-oxide is typically characterized by its molecular formula, which reflects the presence of carbon, hydrogen, nitrogen, and oxygen atoms. The compound is often studied in the context of its role in nucleic acid metabolism and potential implications in mutagenesis and DNA repair processes. Its solubility in various solvents can vary, affecting its reactivity and interaction with other biomolecules. Additionally, guanine 7-oxide may exhibit specific spectral properties, such as UV-Vis absorbance, which can be utilized in analytical chemistry for identification and quantification. Overall, the characteristics of guanine 7-oxide make it a subject of interest in biochemical research, particularly in understanding the effects of oxidative stress on genetic material.
Formula:C5H5N5O2
InChI:InChI=1/C5H5N5O2/c6-5-8-3-2(4(11)9-5)10(12)1-7-3/h1H,(H4,6,7,8,9,11)
Synonyms:
  • Antibiotic 3780
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-, 7-oxide
  • 2-Amino-1,9-dihydro-6H-purin-6-one 7-oxide
  • 2-Amino-3,9-dihydro-6H-purin-6-one 7-oxide
  • guanine 7-oxide
  • Guanine N7-oxide
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-, 7-oxide (9CI)
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  • Guanine-7-oxide

    CAS:
    <p>Guanine-7-oxide (Guanine 7-N-oxide) is an antitumor antibiotic with antitumor and anti-Candida albicans activities. It inhibits the replication of viruses such as herpes virus, infectious hematopoietic necrosis virus (IHNV), and infectious pancreatic necrosis virus (IPNV). The compound also demonstrates significant activity against mouse L1210 leukemia cells.</p>
    Formula:C5H5N5O2
    Color and Shape:Solid
    Molecular weight:167.126