CAS 52286-58-5

Ginsenoside Rf

Description:

Ginsenoside Rf is a natural compound classified as a triterpenoid saponin, primarily found in ginseng species, particularly Panax ginseng. It is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. Ginsenoside Rf is characterized by its complex molecular structure, which includes a steroid-like backbone with various sugar moieties attached, contributing to its biological activity. The compound exhibits solubility in organic solvents and limited solubility in water, typical of many saponins. Its mechanism of action is believed to involve modulation of various signaling pathways, influencing cellular processes such as apoptosis and immune response. Research into Ginsenoside Rf has highlighted its potential therapeutic applications in areas such as cardiovascular health, cognitive function, and metabolic disorders. However, further studies are necessary to fully elucidate its efficacy and safety profile in clinical settings. As with many natural products, the extraction and purification processes can affect the yield and activity of Ginsenoside Rf, making standardization important for research and therapeutic use.

Formula: C₄₂H₇₂O₁₄

InChI: InChI=1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1

InChI key: InChIKey=UZIOUZHBUYLDHW-XUBRWZAZSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@]([C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C1)(C(C)(C)[C@@H](O)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@]6([C@@](CCC=C(C)C)(C)O)[H])[H])[H]

Synonyms:

• (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (6beta,8xi,9xi,12alpha,13alpha,14beta,17beta)-3,12-dihydroxy-17-[(1S,4E)-1-hydroxy-1,5-dimethylhept-4-en-1-yl]-4,4,10,14-tetramethylgonan-6-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Panaxoside RF
• Rf ginsenoside
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• Ginsenoside RF
• β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-
• Ginsenoside Rf

Ginsenoside Rf

CAS: 52286-58-5

Ginsenoside Rf analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₂H₇₂O₁₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 801.03

Ref: 11-0107S

Ginsenoside Rf

CAS: 52286-58-5

Formula: C₄₂H₇₂O₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 801.0127

Ref: IN-DA00D9P3

Ginsenoside Rf

CAS: 52286-58-5

Formula: C₄₂H₇₂O₁₄

Molecular weight: 801.01

Ref: 7W-GC6481

Ginsenoside Rf

CAS: 52286-58-5

Ginsenoside Rf

Purity: ≥98%

Molecular weight: 801.01g/mol

Ref: 54-BUP00986

Ginsenoside Rf

CAS: 52286-58-5

Formula: C₄₂H₇₂O₁₄

Color and Shape: White To Off-White Solid

Molecular weight: 801.02

Ref: 4Z-G-157015

Ginsenoside Rf

CAS: 52286-58-5

GinsenosideRf, as an effective natural product, induces G2/Mphase cell cycle arrest and apoptosis in human osteosarcoma MG-63 cells through the mitochondrial pathway, suggests that it may have a therapeutic effect on human osteosarcoma.

Formula: C₄₂H₇₂O₁₄

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 801.024

Ref: BP-BP0663

Ginsenoside Rf

CAS: 52286-58-5

Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.

Formula: C₄₂H₇₂O₁₄

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 801.01

Ref: TM-T6S1500

Ginsenoside rf

CAS: 52286-58-5

Natural glycoside

Formula: C₄₂H₇₂O₁₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 801.03

Ref: 5G-89213

Ginsenoside Rf

Controlled Product

CAS: 52286-58-5

Applications Ginsenoside Rf is an anti-arthritic agent, attenuating collagen-induced arthritis in mice.
References Jung, S., et al.: Endale, Med. Inflamm., 748964/1 (2014); Wang, H., et al.: J. Pharm. Biomed. Anal., 98, 296 (2014);

Formula: C₄₂H₇₂O₁₄

Color and Shape: White Powder

Molecular weight: 801.01

Ref: TR-G387595

Ginsenoside Rf

CAS: 52286-58-5

Ginsenoside Rf is a steroidal saponin, which is a bioactive compound found primarily in the roots of Panax ginseng, a plant widely used in traditional medicine. As a part of the ginsenoside family, this compound exerts its effects through modulation of several cellular pathways, including anti-inflammatory and antioxidant mechanisms. It is known to interact with glucocorticoid receptors and influence calcium ion channels, contributing to its potential neuroprotective and immunomodulatory effects.

Formula: C₄₂H₇₂O₁₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 801.03 g/mol

Ref: 3D-OG09284

Ginsenoside Rf

CAS: 52286-58-5

Formula: C₄₂H₇₂O₁₄

Molecular weight: 801

Ref: ST-EA-CP-G62005