CAS 52286-59-6

Ginsenoside Re

Description:

Ginsenoside Re is a natural compound classified as a triterpenoid saponin, primarily found in ginseng species, particularly Panax ginseng. It is known for its complex structure, which includes a steroid-like backbone with multiple sugar moieties attached, contributing to its bioactivity. Ginsenoside Re exhibits various pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects, making it a subject of interest in medicinal chemistry and pharmacology. Its mechanism of action often involves modulation of signaling pathways, influencing cellular processes such as apoptosis and proliferation. Additionally, Ginsenoside Re has been studied for its potential benefits in enhancing cognitive function and supporting cardiovascular health. The compound is typically extracted from ginseng roots and can be analyzed using techniques such as high-performance liquid chromatography (HPLC). Due to its therapeutic potential, Ginsenoside Re is often included in dietary supplements and herbal formulations aimed at promoting overall health and wellness. However, further research is necessary to fully elucidate its mechanisms and therapeutic applications.

Formula: C₄₈H₈₂O₁₈

InChI: InChI=1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1

InChI key: InChIKey=PWAOOJDMFUQOKB-WCZZMFLVSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@]([C@@H](O[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@@H](CO)O4)C1)(C(C)(C)[C@@H](O)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@]6([C@@](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)(CCC=C(C)C)C)[H])[H])[H]

Synonyms:

• (3β,6α,12β)-20-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranoside
• 2-O-(6-Desoxy-α-L-mannopyranosyl)-(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-β-D-glucopyranosid
• 2-O-(6-deoxy-α-L-mannopyranosyl)-(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-β-D-glucopyranoside
• 2-O-(6-desoxi-α-L-manopiranosil)-(3β,6α,12β)-20-(β-D-glucopiranosiloxi)-3,12-dihidroxidamar-24-en-6-il-β-D-glucopiranosido
• 2-O-(6-desoxy-α-L-mannopyrannosyl)-(3β,6α,12β)-20-(β-D-glucopyrannosyloxy)-3,12-dihydroxydammar-24-ene-6-yl-β-D-glucopyrannoside
• Chikusetsusaponin IVc
• Ginsenoside B2
• Ginsenoside B₂
• Ginsenoside Re
• Notoginsenoside Re
• Nsc 308877
• Panaxoside Re
• Re ginsenoside
• Sanchinoside Re
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,12β)-20-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-<smallcap>L</span>-mannopyranosyl)-
• 2-O-(6-Deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside
• (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
• (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
• Ginsenoside
• β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
• (3beta,6alpha,9xi,12beta,13alpha)-20-[(3xi)-beta-D-ribo-hexopyranosyloxy]-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₈H₈₂O₁₈

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 947.18

Ref: 11-0103S

Ginsenoside Re

CAS: 52286-59-6

Formula: C₄₈H₈₂O₁₈

Color and Shape: White To Off-White Solid

Molecular weight: 947.17

Ref: 4Z-G-157014

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re

Purity: ≥98%

Molecular weight: 947.15g/mol

Ref: 54-BUP13312

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re, a main phytosterol of Panax ginseng, inhibits Ca(2+) accumulation in mitochondria during cardiac ischemia/reperfusion, which is attributable to nitric oxide (NO)-induced Ca(2+) channel inhibition and K(+) channel activation in cardiac myocytes, acts as a specific agonist for the nongenomic pathway of sex steroid receptors, and NO released from activated eNOS underlies cardiac K(+) channel activation and protection against ischemia-reperfusion injury, G-Re also exerts antiischemic effect and induces angiogenic regeneration.[1,2]

Formula: C₄₈H₈₂O₁₈

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 947.166

Ref: BP-BP0662

Ginsenoside Re

CAS: 52286-59-6

Formula: C₄₈H₈₂O₁₈

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 947.17

Ref: 3B-G0551

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.

Formula: C₄₈H₈₂O₁₈

Purity: 99.12% - >99.99%

Color and Shape: White Powder

Molecular weight: 947.15

Ref: TM-T2872

Ginsenoside Re

CAS: 52286-59-6

Formula: C₄₈H₈₂O₁₈

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 947.15

Ref: 7W-GC5949

Ginsenoside re

CAS: 52286-59-6

Natural glycoside

Formula: C₄₈H₈₂O₁₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 947.17

Ref: 5G-89212

Ginsenoside Re

CAS: 52286-59-6

Applications Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.
References Peng, D. et al.: Chinese Med., 7, 2 (2012); Endale, M. et al.: Med. Inflamm., 748964/1 (2014);

Formula: C₄₈H₈₂O₁₈

Color and Shape: Neat

Molecular weight: 947.15

Ref: TR-G388000

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re is a naturally occurring saponin, which is a bioactive compound sourced primarily from the root of Panax ginseng. It operates through multiple biochemical pathways, including the modulation of immune responses, anti-inflammatory effects, and protective antioxidant activities. Ginsenoside Re exerts its actions by interacting with cellular receptors, influencing signaling pathways such as the PI3K/Akt and MAPK pathways, ultimately impacting gene expression and cellular responses.

Formula: C₄₈H₈₂O₁₈

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 947.18 g/mol

Ref: 3D-OG09285

Ginsenoside Re

CAS: 52286-59-6

Formula: C₄₈H₈₂O₁₈

Molecular weight: 947.17

Ref: ST-EA-CP-G62008