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CAS 52329-60-9

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Aminomebendazole

Description:
Aminomebendazole is a chemical compound that belongs to the class of benzimidazole derivatives, primarily known for its anthelmintic properties, which make it effective against parasitic infections. It is characterized by its ability to inhibit the polymerization of tubulin, thereby disrupting the cytoskeleton of the target organisms. This mechanism of action is similar to that of other benzimidazole compounds, leading to the paralysis and eventual death of the parasites. Aminomebendazole is typically administered in a solid form, and its solubility can vary depending on the pH of the environment. The compound is generally considered to have low toxicity in mammals, making it a suitable option for treating various helminthic infections. Additionally, it may exhibit some antifungal and antibacterial activities, although its primary use remains in the treatment of parasitic diseases. As with any pharmaceutical agent, proper dosage and administration are crucial to maximize efficacy while minimizing potential side effects.
Formula:C14H11N3O
InChI:InChI=1S/C14H11N3O/c15-14-16-11-7-6-10(8-12(11)17-14)13(18)9-4-2-1-3-5-9/h1-8H,(H3,15,16,17)
InChI key:InChIKey=GPMHHSJZGVOEFS-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=C2C(=CC1)N=C(N)N2)C3=CC=CC=C3
Synonyms:
  • (2-Amino-1H-benzimidazol-5-yl)phenylmethanone
  • (2-Amino-1H-benzimidazol-6-yl)phenylmethanone
  • (2-Amino-3H-benzimidazol-5-yl)-phenylmethanone
  • (2-amino-1H-benzimidazol-5-yl)(phenyl)methanone
  • 2-Amino-5-benzoyl-1H-benzimidazole
  • 2-Amino-5-benzoylbenzimidazole
  • Aminomebendazole
  • G 1029
  • R 18986
  • methanone, (2-amino-1H-benzimidazol-5-yl)phenyl-
  • methanone, (2-amino-1H-benzimidazol-6-yl)phenyl-
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