CAS 52336-54-6

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate

Description:

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate, with the CAS number 52336-54-6, is a chemical compound that belongs to the class of phosphorodiamidates. It features a phosphorous atom bonded to two chloroethyl groups and a hydroxypropyl group, which contributes to its unique properties. This compound is characterized by its potential use in agricultural applications, particularly as a pesticide or herbicide, due to its ability to interact with biological systems. The presence of the chloroethyl groups suggests that it may exhibit reactivity, particularly in nucleophilic substitution reactions. Additionally, the hydroxypropyl moiety may enhance its solubility in organic solvents and water, influencing its bioavailability and environmental behavior. Safety considerations are important, as the chloroethyl groups can be toxic and pose health risks. Overall, 3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate is a compound of interest in both chemical research and practical applications, necessitating careful handling and assessment of its environmental impact.

Formula: C₇H₁₇Cl₂N₂O₃P

InChI: InChI=1/C7H17Cl2N2O3P/c8-2-4-11(5-3-9)15(10,13)14-7-1-6-12/h12H,1-7H2,(H2,10,13)

InChI key: InChIKey=BZGFIGVSVQRQBJ-UHFFFAOYSA-N

SMILES: N(P(OCCCO)(N)=O)(CCCl)CCCl

Synonyms:

• Alcophosphamide
• NSC 153182
• NSC 227248
• O-(3-Hydroxypropyl)-N,N-bis(2-chloroethyl)phosphorodiamidate
• Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, 3-hydroxypropyl ester
• 3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate
• Hydroxyphosphamide
• N,N-Bis(2-chloroethyl)phosphorodiaMidic Acid 3-Hydroxypropyl Ester
• Cyclophosphamide Impurity 8 (Alcocyclophosphamide)

Cyclophosphamide Impurity 8 (Alcocyclophosphamide)

CAS: 52336-54-6

Formula: C₇H₁₇Cl₂N₂O₃P

Color and Shape: White To Off-White Solid

Molecular weight: 279.10

Ref: 4Z-C-1023

Alcophosphamide

CAS: 52336-54-6

Alcophosphamide is a urinary metabolite of cyclophosphamide which may be used in proteomics research.

Formula: C₇H₁₇Cl₂N₂O₃P

Color and Shape: Solid

Molecular weight: 279.1

Ref: TM-T29845

Alcophosphamide

Controlled Product

CAS: 52336-54-6

Stability Hygroscopic
Applications Alcophosphamide is a metabolite of the chemotherapeutic agent Cyclophosphamide (C988580).
References Chan, K. et al.: Cancer Res., 54, 6421 (1994); Bates, D.J. et al.: Biochem. Pharmacol., 30, 3055 (1981); Joqueviel, C. et al.: Drug Metab. Dispos., 26, 418 (1998);

Formula: C₇H₁₇Cl₂N₂O₃P

Color and Shape: Neat

Molecular weight: 279.1

Ref: TR-A514575

Alcocyclophosphamide

CAS: 52336-54-6

Formula: C₇H₁₇Cl₂N₂O₃P

Molecular weight: 279.1

Ref: ST-EA-CP-C37037