CymitQuimica logo

CAS 52365-63-6

:

Dipivefrin

Description:
Dipivefrin is a synthetic adrenergic agonist primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It is a prodrug of epinephrine, meaning that it is metabolized in the body to produce epinephrine, which exerts its therapeutic effects. Dipivefrin is characterized by its ability to penetrate the corneal barrier more effectively than epinephrine, enhancing its ocular bioavailability. The substance is typically administered as an eye drop solution. Chemically, it is known for its pivalate ester groups, which contribute to its lipophilicity and stability. Dipivefrin acts primarily on alpha and beta-adrenergic receptors, leading to increased aqueous humor outflow and reduced intraocular pressure. Its pharmacokinetics involve rapid absorption and conversion to epinephrine, with a relatively short duration of action. Side effects may include ocular irritation, increased heart rate, and hypertension, reflecting its systemic adrenergic activity. Overall, dipivefrin represents an important therapeutic option in managing conditions related to elevated intraocular pressure.
Formula:C19H29NO5
InChI:InChI=1S/C19H29NO5/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6/h8-10,13,20-21H,11H2,1-7H3
InChI key:InChIKey=OCUJLLGVOUDECM-UHFFFAOYSA-N
SMILES:O(C(C(C)(C)C)=O)C1=C(OC(C(C)(C)C)=O)C=CC(C(CNC)O)=C1
Synonyms:
  • (.+-.)-Dipivefrin
  • (±)-3,4-Dihydroxy-a-[(methylamino)methyl]benzyl Alcohol 3,4-Dipivalate
  • 1-(3',4'-Dipivaloyloxyphenyl)-2-methylamino-1-ethanol
  • 2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester
  • 4-[1-Hydroxy-2-(Methylamino)Ethyl]Benzene-1,2-Diyl Bis(2,2-Dimethylpropanoate)
  • 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene bis(2,2-dimethylpropanoate)
  • 52365-63-6
  • DPE
  • Dipivalyl Epinephrine
  • Propanoic Acid, 2,2-Dimethyl-, 4-[1-Hydroxy-2-(Methylamino)Ethyl]-1,2-Phenylene Ester
  • See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 4 products.