CAS 52443-21-7

Glucametacin

Description:

Glucametacin, with the CAS number 52443-21-7, is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of indole acetic acid derivatives. It is primarily used for its analgesic and anti-inflammatory properties, making it effective in treating conditions such as arthritis and other inflammatory disorders. The compound exhibits a mechanism of action that involves the inhibition of cyclooxygenase (COX) enzymes, which play a crucial role in the biosynthesis of prostaglandins, mediators of inflammation and pain. Glucametacin is characterized by its relatively high lipophilicity, which can influence its absorption and distribution in the body. The drug is typically administered orally and may be available in various formulations, including tablets or capsules. As with other NSAIDs, potential side effects may include gastrointestinal disturbances, cardiovascular risks, and renal impairment, necessitating careful consideration of patient history and concurrent medications. Overall, glucametacin serves as a valuable therapeutic option in the management of pain and inflammation.

Formula: C₂₅H₂₇ClN₂O₈

InChI: InChI=1S/C25H27ClN2O8/c1-13-17(10-22(32)27-19(11-29)23(33)24(34)21(31)12-30)18-9-16(36-2)7-8-20(18)28(13)25(35)14-3-5-15(26)6-4-14/h3-9,11,19,21,23-24,30-31,33-34H,10,12H2,1-2H3,(H,27,32)/t19-,21+,23+,24+/m0/s1

InChI key: InChIKey=XLVXAUNDHWERBM-IVGWJTKZSA-N

SMILES: C(=O)(N1C=2C(C(CC(N[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)C=O)=O)=C1C)=CC(OC)=CC2)C3=CC=C(Cl)C=C3

Synonyms:

• 2-({[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}amino)-2-deoxy-D-glucose
• 2-[({1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetyl)amino]-2-deoxy-D-glucose
• 2-[2-[1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamido]-2-deoxy-D-glucose
• 2-[[2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-<span class="text-smallcaps">D</span>-glucose
• 257-923-9
• <span class="text-smallcaps">D</span>-Glucose, 2-[[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-
• <span class="text-smallcaps">D</span>-Glucose, 2-[[[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-
• Glucametacine
• Glucamethacin
• Indomethacin Glucosamide
• 2-[[2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-D-glucose
• D-Glucose, 2-[[[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-
• D-Glucose, 2-[[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-

Glucametacine

CAS: 52443-21-7

Glucametacine is an anti-inflammatory agent.

Formula: C₂₅H₂₇ClN₂O₈

Color and Shape: Solid

Molecular weight: 518.94

Ref: TM-T63619