CAS 52476-66-1

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

Description:

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine is a heterocyclic organic compound characterized by its pyrimidine and pyrazole moieties. The presence of a chlorine atom at the 2-position and a 3,5-dimethyl-1H-pyrazole group at the 4-position contributes to its unique chemical properties. This compound typically exhibits moderate to high solubility in polar organic solvents, while its solid state may present as a crystalline or amorphous form. It is often utilized in medicinal chemistry and agricultural applications, particularly as a building block in the synthesis of biologically active compounds. The presence of the pyrazole ring can impart specific biological activities, making it of interest in drug discovery. Additionally, the chlorine substituent can enhance the compound's reactivity and stability, influencing its interactions in various chemical environments. Safety data should be consulted for handling, as with many halogenated compounds, it may pose certain health and environmental risks.

Formula: C₉H₉ClN₄

InChI: InChI=1S/C9H9ClN4/c1-6-5-7(2)14(13-6)8-3-4-11-9(10)12-8/h3-5H,1-2H3

InChI key: InChIKey=ZAEUNAXJMQKCCG-UHFFFAOYSA-N

SMILES: CC=1N(C2=NC(Cl)=NC=C2)N=C(C)C1

Synonyms:

• 2-Chloro-4-(3,5-dimethylpyrazol-1-yl)pyrimidine
• 2-Chloro-4-(3,5-dimethyl-pyrazol-1-yl)-pyrimidine
• Pyrimidine, 2-chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)-
• 2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

CAS: 52476-66-1

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

Purity: 95%

Molecular weight: 208.65g/mol

Ref: 54-OR1048463

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine

CAS: 52476-66-1

2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine is an inhibitor of DNA polymerase. It has been shown to be a potent inhibitor of the synthesis of dna and protein in bacterial cells. 2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine forms two types of interactions with the enzyme: intermolecular interactions with the enzyme's active site, which prevents substrate binding, and intramolecular interactions with residues on the enzyme's surface, which inhibits catalysis. The crystal structure shows that hydrogen bonds form between the inhibitory molecule and amino acid residues on the enzyme's surface.

Formula: C₉H₉ClN₄

Purity: Min. 95%

Molecular weight: 208.65 g/mol

Ref: 3D-CCA47666