CAS 52549-17-4

(±)-Pranoprofen

Description:

(±)-Pranoprofen is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is classified as a propionic acid derivative and is known for its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins involved in inflammation and pain signaling. The substance exists as a racemic mixture, containing both the R and S enantiomers, which can exhibit different pharmacological effects. (±)-Pranoprofen is typically administered orally and is utilized in the treatment of conditions such as arthritis and other inflammatory disorders. Its chemical structure includes a carboxylic acid functional group, contributing to its acidic nature. The compound is generally well-absorbed in the gastrointestinal tract, with its pharmacokinetics influenced by factors such as dosage and formulation. As with many NSAIDs, potential side effects may include gastrointestinal discomfort, cardiovascular risks, and renal impairment, necessitating careful consideration in patients with pre-existing conditions.

Formula: C₁₅H₁₃NO₃

InChI: InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18)

InChI key: InChIKey=TVQZAMVBTVNYLA-UHFFFAOYSA-N

SMILES: C(C(O)=O)(C)C=1C=C2C(OC=3C(C2)=CC=CN3)=CC1

Synonyms:

• (RS)-Pranoprofen
• 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid
• 2-(5H-[1]Benzopyrano[2,3-b]pyridin-7-yl)propionic Acid
• 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, α-methyl-
• 5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid, alpha-methyl-
• Niflan
• Oftalar
• Y 8004
• a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic Acid
• dl-Pranoprofen
• α-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid

Pranoprofen (α-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid)

CAS: 52549-17-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₅H₁₃NO₃

Color and Shape: White Off-White Solid

Molecular weight: 255.08954

Ref: 45-1554013

Pranoprofen

CAS: 52549-17-4

Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.

Formula: C₁₅H₁₃NO₃

Purity: 97.98% - 99.85%

Color and Shape: Solid

Molecular weight: 255.27

Ref: TM-T0159

2-(5H-Chromeno[2,3-B]Pyridin-7-Yl)Propanoic Acid

CAS: 52549-17-4

2-(5H-Chromeno[2,3-B]Pyridin-7-Yl)Propanoic Acid

Purity: 99%

Molecular weight: 255.27g/mol

Ref: 54-OR1009788

Pranoprofen

CAS: 52549-17-4

Pranoprofen

Purity: ≥95%

Molecular weight: 255.27g/mol

Ref: 54-BUP15124

Pranoprofen

CAS: 52549-17-4

Formula: C₁₅H₁₃NO₃

Molecular weight: 255.27

Ref: 7W-GP7370

Pranoprofen-13C-d3

CAS: 52549-17-4

Formula: C₁₄₁₃CH₁₀D₃NO₃

Molecular weight: 259.28

Ref: 4Z-P-11009

Pranoprofen

CAS: 52549-17-4

Formula: C₁₅H₁₃NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 255.27

Ref: 4Z-P-11001

Pranoprofen

CAS: 52549-17-4

Formula: C₁₅H₁₃NO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 255.27

Ref: 3B-P2778

Pranoprofen

Controlled Product

CAS: 52549-17-4

Applications Pranoprofen is an anti-inflammatory used in ophthalmology.
References Ayaki, M., et al.: Biocont. Sci., 15, 97 (2010); Lee, X., et al.: For. Toxicol., 28, 96 (2010);

Formula: C₁₅H₁₃NO₃

Color and Shape: Off White Crystalline

Molecular weight: 255.27

Ref: TR-P701140

Pranoprofen

CAS: 52549-17-4

Inhibitor of COX-1 and COX-2 cyclooxygenases

Formula: C₁₅H₁₃NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 255.27 g/mol

Ref: 3D-FM27121

Pranoprofen-d3

Controlled Product

CAS: 52549-17-4

Formula: C₁₅D₃H₁₀NO₃

Color and Shape: Neat

Molecular weight: 258.287

Ref: TR-P701142