CAS 5255-33-4

4-Methyl-5-thiazoleacetic acid

Description:

4-Methyl-5-thiazoleacetic acid is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing sulfur and nitrogen. This compound features a methyl group and a carboxylic acid functional group, contributing to its acidic properties. It is typically a white to off-white crystalline solid, soluble in water and various organic solvents, which makes it useful in different chemical applications. The presence of the thiazole moiety imparts unique biological activities, making it of interest in pharmaceutical research. Its CAS number, 5255-33-4, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. 4-Methyl-5-thiazoleacetic acid may also exhibit potential as a building block in organic synthesis, particularly in the development of agrochemicals or pharmaceuticals. As with many organic acids, it can participate in various chemical reactions, including esterification and amidation, further expanding its utility in synthetic chemistry.

Formula: C₆H₇NO₂S

InChI: InChI=1S/C6H7NO2S/c1-4-5(2-6(8)9)10-3-7-4/h3H,2H2,1H3,(H,8,9)

InChI key: InChIKey=BHYWREOEQYCKSC-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=C(C)N=CS1

Synonyms:

• (4-Methyl-1,3-Thiazol-5-Yl)Acetic Acid
• 2-(4-Methyl-1,3-thiazol-5-yl)acetic acid
• 2-(4-Methylthiazol-5-yl)acetic acid
• 4-Methyl-5-thiazoleacetic acid
• 5-Thiazoleacetic acid, 4-methyl-
• Acide methyl-4 thiazole-acetique-5
• Acide methyl-4 thiazole-acetique-5 [French]
• Brn 0120919
• 4-Methylthiazol-5-acetic acid
• 4-27-00-04018 (Beilstein Handbook Reference)

4-Methyl-5-thiazoleacetic acid

CAS: 5255-33-4

Formula: C₆H₇NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 157.1903

Ref: IN-DA003EX1

2-(4-Methyl-1,3-thiazol-5-yl)acetic acid

CAS: 5255-33-4

Purity: ≥95%

Molecular weight: 157.1900024

Ref: 10-F718361

4-Methyl-5-thiazoleacetic acid

CAS: 5255-33-4

4-Methyl-5-thiazoleacetic acid (MTAA) is a metabolite of chlormethiazole. It has been shown to have similar pharmacological properties as the parent drug, including analgesic, anti-inflammatory and antiemetic effects. MTAA is excreted quantitatively in urine and has been detected as an endogenous metabolite in humans. Gas chromatography with mass spectrometry was used to analyze human urine samples for MTAA and its metabolites. The metabolism of MTAA has been studied by extracting rat liver homogenates, analyzing them for MTAA, and determining the metabolic products that were found in the extractions. These studies show that 4-methyl-5-thiazoleacetic acid is metabolized to produce a number of metabolites, including edisylate, which is also an active metabolite of chlormethiazole.

Formula: C₆H₇NO₂S

Purity: Min. 95%

Molecular weight: 157.19 g/mol

Ref: 3D-FAA25533