CAS 52605-52-4

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride (1:1)

Description:

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride, with the CAS number 52605-52-4, is a chemical compound that belongs to the piperazine class of compounds. It features a piperazine ring substituted with a 3-chlorophenyl group and a 3-chloropropyl group, which contributes to its unique pharmacological properties. This compound is typically encountered as a hydrochloride salt, enhancing its solubility in water and making it suitable for various applications, including research in pharmacology and medicinal chemistry. The presence of chlorine atoms in its structure may influence its biological activity and interaction with receptors. As a piperazine derivative, it may exhibit properties related to neurotransmitter modulation, potentially impacting serotonin and dopamine pathways. However, specific biological activities, toxicity, and safety profiles would require further investigation through empirical studies. Overall, this compound represents a significant interest in the field of drug development and chemical research, particularly in exploring its potential therapeutic applications.

Formula: C₁₃H₁₈Cl₂N₂·ClH

InChI: InChI=1S/C13H18Cl2N2.ClH/c14-5-2-6-16-7-9-17(10-8-16)13-4-1-3-12(15)11-13;/h1,3-4,11H,2,5-10H2;1H

InChI key: InChIKey=JVLRNANYLVRULL-UHFFFAOYSA-N

SMILES: ClC=1C=C(N2CCN(CCCCl)CC2)C=CC1.Cl

Synonyms:

• 1-(3-Chloropheny)-4-(3-Chloropropyl) Piperazine Hydrochloride
• 1-(3-Chlorophenyl)-4-(3-3-Chloropropyl) Piperazine Hcl
• 1-(3-Chlorophenyl)-4-(3-Chloropropyl) Piperazine Hcl
• 1-(3-Chlorophenyl)-4-(3-Chloropropyl)Piperazin-1-Ium Chloride
• 1-(3-Chlorophenyl)-4-(3-Chloropropyl)Piperazine Monohydrochloride
• 1-(3-Chlorophenyl)-4-(3-Chloroproyl)Piperazine Hydrochloride
• 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride (1:1)
• 1-(3-Chloropropyl)-4-(3-Chlorophenyl)Piperazine Hcl
• 1-(Chloropropyl)-4-(3-Chlorophenyl) Piperazine
• Ccp Hcl
• Labotest-Bb Lt00138222
• Piperazine, 1-(3-chlorophenyl)-4-(3-chloropropyl)-, hydrochloride (1:1)
• Piperazine, 1-(3-chlorophenyl)-4-(3-chloropropyl)-, monohydrochloride

Trazodone Related Compound F (1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride)

CAS: 52605-52-4

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoi

Formula: C₁₃H₁₈Cl₂N₂·ClH

Color and Shape: White Powder

Molecular weight: 308.06138

Ref: 45-1673566

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride

CAS: 52605-52-4

Formula: C₁₃H₁₉Cl₃N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 309.6624

Ref: IN-DA003AZ8

Trazodone USP Related Compound F

CAS: 52605-52-4

Formula: C₁₃H₁₈Cl₂N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 273.20 36.46

Ref: 4Z-T-338

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride

CAS: 52605-52-4

Ref: 7W-GK0988

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride

CAS: 52605-52-4

Formula: C₁₃H₁₈Cl₂N₂·HCl

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 309.66

Ref: 3B-C1608

Trazodone EP Impurity F (as Hydrochloride)

Controlled Product

CAS: 52605-52-4

Formula: C₁₃H₁₈Cl₂N₂·ClH

Color and Shape: Neat

Molecular weight: 309.66

Ref: 86-MM0421.06

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride

Controlled Product

CAS: 52605-52-4

Impurity Trazodone USP Related Compound F
Applications An arylpiperazine compound which is an important intermediate in the preparation of various pharmaceuticals, such as Trazodone (T718500), used to treat depression and post-traumatic stress. Trazodone impurity F. Trazodone USP Related Compound F.
References Oshiro, Y. et al.: J. Med. Chem., 43, 177 (2000); Van Wijk, A.M. et al.: Anal. Bioanal. Chem., 400, 1375 (2011);

Formula: C₁₃H₁₈Cl₂N₂·ClH

Color and Shape: Neat

Molecular weight: 309.66

Ref: TR-C377720

Trazodone USP Related Compound F

CAS: 52605-52-4

Formula: C₁₃H₁₈Cl₂N₂HCl

Molecular weight: 273.20 : 36.46

Ref: ST-EA-CP-T29012

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride

Controlled Product

CAS: 52605-52-4

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride is an antidepressant that belongs to the class of nefazodone. It is a prodrug, which is hydrolyzed to nefazodone in the liver. It has been shown to have a high affinity for serotonin receptors and as such may be useful for the treatment of depression. 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride also has anticonvulsant properties, which may be due to its inhibition of neuronal excitability by blocking sodium channels in the brain.

Formula: C₁₃H₁₈Cl₂N₂·HCl

Purity: Min. 95%

Molecular weight: 309.66 g/mol

Ref: 3D-FC75434