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CAS 526182-94-5

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Piperidine, 2-[2-(trifluoromethyl)phenyl]-

Description:
Piperidine, 2-[2-(trifluoromethyl)phenyl]- is a chemical compound characterized by its piperidine ring, which is a six-membered saturated heterocycle containing one nitrogen atom. The presence of a trifluoromethyl group (-CF3) attached to a phenyl ring significantly influences its chemical properties, including its reactivity and polarity. This compound typically exhibits a moderate to high level of lipophilicity due to the hydrophobic nature of the trifluoromethyl group, which can enhance its ability to penetrate biological membranes. The trifluoromethyl group also contributes to the compound's stability and can affect its interaction with various biological targets. Piperidine derivatives are often studied for their potential applications in pharmaceuticals, particularly in the development of drugs targeting neurological and psychiatric disorders. The compound's molecular structure suggests it may participate in hydrogen bonding and other intermolecular interactions, which are critical for its biological activity. Safety and handling precautions should be observed, as with many organic compounds, due to potential toxicity and environmental impact.
Formula:C12H14F3N
InChI:InChI=1/C12H14F3N/c13-12(14,15)10-6-2-1-5-9(10)11-7-3-4-8-16-11/h1-2,5-6,11,16H,3-4,7-8H2
SMILES:c1ccc(c(c1)C1CCCCN1)C(F)(F)F
Synonyms:
  • 2-[2-(Trifluoromethyl)phenyl]piperidine
  • piperidine, 2-[2-(trifluoromethyl)phenyl]-
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