CAS 52619-18-8

Pregna-1,4-diene-3,20-dione, 9-chloro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16β)-

Description:

Pregna-1,4-diene-3,20-dione, 9-chloro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16β)-, identified by the CAS number 52619-18-8, is a synthetic steroid compound that exhibits characteristics typical of glucocorticoids and progestins. This compound features a steroid backbone with multiple functional groups, including hydroxyl (-OH) groups, a chloro substituent, and an ether linkage, which contribute to its biological activity. The presence of the 1,4-diene structure indicates potential reactivity and stability under certain conditions. Its specific stereochemistry, denoted by the (11β,16β) configuration, is crucial for its interaction with biological receptors, influencing its pharmacological effects. This compound may be investigated for its potential therapeutic applications, particularly in the fields of endocrinology and reproductive health, due to its structural similarities to naturally occurring hormones. However, detailed studies on its pharmacodynamics, pharmacokinetics, and safety profile are essential for understanding its full potential and implications in medical use.

Formula: C₂₇H₃₇ClO₆

InChI: InChI=1S/C27H37ClO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=CYBACPSHBXABHX-SUYDQAKGSA-N

SMILES: C[C@@]12[C@@](OC(CCCC)=O)(C(CO)=O)[C@@H](C)C[C@]1([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (11Beta,16Beta)-9-Chloro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
• 258-050-6
• Pregna-1,4-diene-3,20-dione, 9-chloro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16β)-

BETAMETHASONE VALERATE IMPURITY MIXTURE CRS

CAS: 2802-10-0, 33755-46-3, 52619-18-8

BETAMETHASONE VALERATE IMPURITY MIXTURE CRS

Ref: 41-Y0001065

(8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate (Betamethasone Valerate Impurity)

CAS: 52619-18-8

(8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate (Betamethasone Valerate Impurity)

Purity: 98%

Ref: 54-OR1039897

Betamethasone Valerate EP Impurity H

CAS: 52619-18-8

Formula: C₂₇H₃₇ClO₆

Color and Shape: White To Off-White Solid

Molecular weight: 493.04

Ref: 4Z-B-065011

Beclomethasone 17-Valerate

CAS: 52619-18-8

Impurity Betamethasone Valerate EP Impurity H
Applications Beclomethasone 17-Valerate (Betamethasone Valerate EP Impurity H) is a derivative of Beclomethasone (B131000), an glucocorticord used in chronic asthma and allergic rhinitis.
References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),

Formula: C₂₇H₃₇ClO₆

Color and Shape: Neat

Molecular weight: 493.03

Ref: TR-B131065

9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-valerate

Controlled Product

CAS: 52619-18-8

Prednisolone is a synthetic corticosteroid that is used in the treatment of a number of lung diseases, including asthma. Prednisolone is used to decrease the inflammation and swelling around the airways and lungs. Prednisolone is used to treat certain skin conditions, such as eczema and dermatitis. This drug also decreases the activity of the immune system by inhibiting production of substances that cause inflammation. The onset of action for prednisolone is typically one day with a duration of up to two weeks. It has been shown to be more effective when taken orally than when applied topically. It may be taken with or without food and can be given as an oral or an intravenous dose. Prednisolone tablets must be dissolved in water before they are placed under the tongue (sublingual). The tablets will dissolve quickly under the tongue, releasing prednisolone into your bloodstream. Enteric-coated tablets should not be crushed or chewed

Formula: C₂₇H₃₇ClO₆

Purity: Min. 95%

Molecular weight: 493.03 g/mol

Ref: 3D-FC156893

Betamethasone Valerate EP Impurity H

CAS: 52619-18-8

Formula: C₂₇H₃₇ClO₆

Molecular weight: 493.04

Ref: ST-EA-CP-B5008